Non-motor Symptoms, Sleep Disturbances, And Genetic Insights In Young Onset Parkinson’s Disease: A Prospective Descriptive Study
Objective: 1. To study the prevalence of various non-motor symptoms in Young onset Parkinson's Disease patients2. To study the genetic markers in YOPD patients. Background:…Gene Polymorphisms of Parkinson’s Disease risk locus and idiopathic REM Sleep Behavior Disorder
Objective: Genetic factors play an important role in idiopathic rapid eye movement sleep behavior disorder (iRBD) but have not been fully studied. Background: This study…Rare Variants in RAB GTPases in Parkinson’s Disease
Objective: To investigate variants across the RAB GTPase genes in Parkinson’s disease (PD). Background: The Global Parkinson’s Genetics Program (GP2, http://gp2.org/) is an international collaborative…Applying growth mixture models to elucidate heterogeneous trajectories of cognitive change in Parkinson’s Disease
Objective: To apply growth mixture models (GMM) to elucidate heterogeneity in cognitive change trajectories in Parkinson’s Disease (PD) among idiopathic PD (iPD), GBA1, and LRRK2…Subthalamic Nucleus Stimulation May Suppress Both Ipsilateral and Contralateral Local-Field-Potential Magnitude
Objective: Determine whether ipsilateral subthalamic nucleus (STN) stimulation affects local field potential (LFP) power in the contralateral STN to inform clinical decision making. Background: A…Low Frequency Directional Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-Resistant Freezing of Gait: Six-Month Outcomes.
Objective: This is a prospective, open-label, single-arm study to assess safety and efficacy of cuneiform(CnF) deep brain stimulation(DBS) in Parkinson's disease(PD) patients with levodopa-refractory freezing…Deep Brain Stimulation for Early-Onset Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To evaluate clinical outcomes in patients with Early-Onset Parkinson’s Disease (EOPD) treated with deep brain stimulation (DBS) Background: EOPD is defined as Parkinson’s disease…STN-DBS Improves Motor and Cognitive Functions Associated with Increased Occipital Metabolism in PDD Patients
Objective: The study aims to determine whether STN-DBS brings about clinical benefits for Parkinson’s disease dementia (PDD) patients and its association with metabolic change in…Evaluation of Nociception in a Model of Parkinson’s Disease for the Study of Non-Motor Symptoms in Trpv4-/- Animals
Objective: This study aimed to investigate the role of the TRPV4 receptor in regulating the nociception in a PD model experimental for the study of…Globus pallidus interna deep brain stimulation for Parkinson’s Disease: Impact on Restless Legs Syndrome
Objective: This study evaluated one-year outcomes of Restless Legs Syndrome (RLS) in a cohort of patients with Parkinson’s disease (PD) who underwent deep brain stimulation…
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