VPS35-Related Parkinson Disease in a Patient of Korean Ancestry: A Case Report
Objective: To report a case of a 65-year-old Korean woman diagnosed with a rare gene mutation involving VPS35 linked to Parkinson’s disease (PD). Background: Major…Genetic variants detection and prevalence in Hawaii’s diverse PD population
Objective: To overcome access barriers to genetic testing and address the paucity of knowledge regarding genetic causes of PD among Hawaii’s racial and ethnic groups.…Unveiling Parkinson’s Disease Variants in the Chinese Population: The CPD10KGP Study
Objective: In response to these limitations, we are proposing the China Parkinson’s Disease 10,000 Genomes Project (CPD10KGP), which aims to delineate the genetic architecture of…Parameterization of Intraoperative Human Microelectrode Recordings: Linking Action Potential Morphology to Brain Anatomy
Objective: To investigate whether single-unit spike morphology from intraoperative microelectrode recordings (MER) can provide anatomical and physiological insights relevant to deep brain stimulation (DBS) targeting.…Magnetic Resonance Guided Focused Ultrasound for Essential Tremor and Tremor dominant Parkinson’s Disease Case Series
Objective: To assess the efficacy and safety of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) for Essential Tremor (ET) and Tremor Dominant Parkinson's Disease (TDPD) in…DBS Withdrawal Syndrome in Advanced Parkinson’s Disease: A Case Series
Objective: Deep Brain Stimulation (DBS) is a widely used neuromodulation therapy for managing motor complications in advanced Parkinson’s disease (PD). However, abrupt cessation of DBS,…Stimulation-Entrained Gamma-Driven Adaptive DBS Improves Motor Diary Reports of Symptom Fluctuations in Parkinson’s Disease
Objective: To compare adaptive deep brain stimulation (aDBS) using stimulation-entrained gamma oscillations as a feedback signal to conventional constant-amplitude deep brain stimulation (cDBS) using validated…Distinguishing DBS and Non-DBS Parkinson’s Patients Using Recurrence Plots and Vision Transformers
Objective: To introduce an innovative method for distinguishing gait patterns in Parkinson’s Disease (PD) patients with medical or surgical treatment and healthy controls, by exploiting…Novel Technologies for REM Sleep Behavior Disorder Detection to Identify Prodromal Parkinson’s Disease at Home
Objective: Isolated REM sleep behavior disorder (RBD) is a strong prodromal marker of Parkinson’s disease (PD) and related alpha-synucleinopathies. Early identification is crucial for timely…The effect of continuous subcutaneous foslevodopa/foscarbidopa infusion on sleep in Parkinson’s disease: three case reports
Objective: To assess the effect of continuous subcutaneous infusion of foslevodopa/foscarbidopa (LDP/CDP) on sleep in a patient with Parkinson’s disease (PD). Background: Continuous subcutaneous infusion…
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