Qualitative research in advanced Parkinson’s disease: Exploring salient symptoms and suitability of the MDS-NMS from the patient, caregiver, and clinician perspective
Objective: To identify which non-motor symptoms (NMS) are most relevant in an advanced Parkinson’s Disease (PD) population and determine the suitability of the International Parkinson…Transcranial direct current stimulation combined with motor training for motor symptoms in Parkinson’s disease: a systematic review and meta-analysis
Objective: We aimed to compare the acute and retention effects of motor training alone versus its combination with transcranial direct current stimulation (tDCS) on motor…Dose Optimization of Foslevodopa/Foscarbidopa: Post Hoc Analysis of Study Completers
Objective: To describe dose optimization, efficacy, and safety of foslevodopa/foscarbidopa (LDp/CDp) in patients with advanced Parkinson’s disease (PwaPD) who completed a 52-week open-label study. Background:…Opicapone in Parkinson’s Patients with Probable REM Sleep Behavior Disorder: Insights from the OASIS Trial
Objective: To evaluate opicapone’s effect on sleep disturbances, motor and non-motor symptoms and quality of life in Parkinson's disease (PD) patients with and without probable…SL-START: A Multicentre Observational Study of Sublingual Apomorphine Titration and Usage Schemes in Routine Practice
Objective: A patient’s early experience with a new medication is critical to medication adherence and overall treatment outcomes. The SL-START study aims to characterize how…Adaptive deep brain stimulation for tremor control in Parkinson’s disease
Objective: To evaluate clinical improvements in tremor following the implementation of adaptive deep brain stimulation (aDBS). Background: Alpha-beta (8-30Hz) based aDBS is a safe and…Evaluation of Local Field Potential-guided DBS-programming in a Parkinson’s disease outpatient clinic
Objective: To evaluate potential use and applicability of local field potential-guided DBS-programming under real-life conditions in a Parkinson’s disease (PD) outpatient clinic. Background: Deep brain…EJS ACT-PD: An Ongoing Initiative to Support Innovation and Sustainability of a Multi-Arm, Multi-Stage Platform Trial for Parkinson’s Disease
Objective: To provide continued consortium expertise to provide ongoing innovation and long-term sustainability in a multi-arm, multi-stage (MAMS) disease modification trial for Parkinson’s disease (PD).…Continued Evaluation of Bemdaneprocel Following a Phase 1 Study for Parkinson’s Disease: Outcomes Through 3 Years
Objective: To report the safety and clinical outcomes of bemdaneprocel in participants with Parkinson’s disease (PD) through 3 years post transplantation. Background: Bemdaneprocel is an…Computer Vision Quantification of Repeated Finger Tapping Demonstrates Aberrant Plasticity in Parkinson’s Disease
Objective: Test if symptoms of Parkinson's disease (PD) develop through aberrant plasticity. Background: Recent results in 6-hydroxydopamine-lesioned mice show that repeated performance of simple motor…
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