Early Indicators of Alpha-synuclein Aggregation: Can Autonomic and Cognitive Markers Predict Prodromal Parkinson’s Disease?
Objective: To develop a model that predicts alpha synuclein (a-syn) status of patients at risk of Parkinson’s disease (PD) using non-motor and cognitive tests that…Real-life experience with continuous subcutaneous foslevodopa/foscarbidopa infusion in advanced stage of Parkinson’s disease at Villa Margherita
Objective: We present the results of our case series with continuous subcutaneous infusion (CSCI) produodopa in 2024, focusing on tolerability and efficacy, in line with…Muscle Interactions during Gait in People with Parkinson’s Disease
Objective: To study modulation and asymmetry in lower limb muscles in individuals with Parkinson’s Disease (PD), compared to healthy controls (HC). Background: Walking disorders are…Examining the Influence of Task Complexity on Dual Task Performance in Parkinson’s disease.
Objective: This study aimed to examine the impact of walking task complexity and cognitive speaking task (CST) condition on dual-task effects (DTE) in people with…Health Disparity in Rural Southern California
Objective: To analyze the demographic and clinical characteristics of hispanic patients with Parkinson's disease in rural southern California Background: Parkinson’s disease (PD) is the second…Association Between Trait Impulsivity and Freezing of Gait in People with Parkinson’s Disease
Objective: To analyze the association between motor, attentional and non-planning impulsivity and freezing of gait in people with PD Background: Freezing of gait is a…Quality of Life of Parkinson’s Disease Patients in the Thai Population: A Cross-Sectional Analysis
Objective: Primary: To assess QoL in PD patients at the Neurological Institute of Thailand (NIT).Secondary: To identify clinical factors associated with QoL. Background: Parkinson’s disease…Evaluating the Efficacy of Home-Based Exercise Interventions for Individuals with Mild to Moderate Parkinson’s Disease: A Systematic Review
Objective: To systematically evaluate the effectiveness of HBEI on motor symptoms, balance, and overall well-being in individuals with mild to moderate PD, providing insights into…LRRK2 I1371V Mutation Induces ER Stress, Mitochondrial Dysfunction, and Impaired Mitophagy in Parkinson’s Disease Astrocytes
Objective: This study examines the pathogenic effect of the LRRK2 I1371V mutation on mitochondrial dysfunction, as a result of ER calcium dysregulation, and impaired mitophagy…Metabolomic Profiling in an Egyptian Cohort Reveals Altered Phenylalanine Metabolism and Suggests a Role for Trans-Cinnamate in Parkinson Disease
Objective: Investigate the associated metabolic changes in PD via a comprehensive metabolic analysis with a focus on phenylalanine (dopamine precursor) metabolism and its impact on…
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