Prognostic Impact of GBA Variants on Mortality in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: This systematic review and meta-analyses aim to synthesize longitudinal evidence of GBA variants as a prognostic factor for all-cause mortality in Parkinson’s disease (PD).…Late-Onset Ataxia, Tremor and Spastic Paraparesis associated with the a Novel CCDC88C Variant: Expanding the Phenotypic Spectrum of mutation in the CCDC88C gene
Objective: to describe a Croatian family presenting with late-onset spastic paraparesis and cognitive decline associated with a distinct amino acid substitution. Background: Variants in CCDC88C…Proximity Ligation Assay Reveals Early Tractopathy in Parkinson’s Disease
Objective: To determine how α-synuclein (αSyn) pathology extends beyond the neuronal soma in the anterior cingulate cortex (ACC) by mapping early pathological changes within adjacent…Advancing Regular Non-motor Symptom Reporting During Inpatient Parkinson’s Disease Care Using a Self-Developed Digital Diary: A Three-Cohort Engagement Evaluation
Objective: To establish a robust digital approach that encourages hospitalized Parkinson’s disease (PD) patients to self-report non-motor symptoms throughout inpatient care, and to determine whether…Sleep Architecture and Cognitive Performance in Early Huntington’s Disease: A Pilot Study
Objective: Characterize sleep architecture and cognitive performance in people with early Huntington’s disease (HD) and explore their associations. Background: Cognitive impairment is a devastating feature…Challenges of Translating the MDS-UPDRS into Ukrainian During Wartime
Objective: To describe the practical, linguistic, and logistical challenges encountered during the Ukrainian translation and cultural adaptation of the MDS-UPDRS. Background: The process of translating…Emergence of Cortical Amyloid from the Prodromal Stage of the Lewy Body Disease Spectrum: Evidence from a PiB-PET Study
Objective: To characterize β-amyloid (Aβ) deposition across the Lewy body disease (LBD) spectrum using Pittsburgh compound B positron emission tomography (PiB-PET) and examine the influence…Physiotherapists’ Clinical Reasoning When Selecting Compensatory Strategies for Gait Impairments in Parkinson’s Disease
Objective: To examine physiotherapists’ understanding of compensatory strategies and how they select them for gait impairments in people with Parkinson’s disease (PwP). Background: Compensatory strategies…Mechanical Ventilation Modifies the Natural History of DCTN1 p.G71A Perry Disease: A 20-Year Longitudinal Study
Objective: To determine whether mechanical ventilation modifies survival and disease trajectory in an expanded Japanese pedigree with DCTN1 p.G71A–related Perry disease. Background: Perry disease is…Structural-Functional Decoupling and Imaging Transcriptomics in Cognitive Impairment of Parkinson’s Disease
Objective: To examine SDI across cognitive stages of Parkinson’s disease (PD) and its associations with cortical thickness (CTh), cognition, and cell-type transcriptomic signatures. Background: Cognitive…
- « Previous Page
- 1
- …
- 110
- 111
- 112
- 113
- 114
- …
- 208
- Next Page »