Local Field Potentials (LFP) Insights in the Treatment of X-linked Dystonia-Parkinsonism with Deep Brain Stimulation of the Subthalamic Nucleus
Objective: To demonstrate sustained improvement in parkinsonism and dystonia in patients with X-linked Dystonia-Parkinsonism (XDP) after deep brain stimulation (DBS) of the subthalamic nucleus (STN)…Evaluating the Stability of a Short Smell Test in the PREDICT-PD Cohort
Objective: To evaluate the stability of a 6-item smell test, in the context of a prodromal Parkinson’s (PD) cohort. Background: Short smell tests have been…The Nature of autonomic dysfunction and its relationship with motor symptoms in Drug-Naive Parkinson’s Disease Patients: Korean Cohort Data
Objective: We aimed to characterize the domain-specific distribution of autonomic symptoms in newly diagnosed, drug-naive PD and to investigate whether distinct autonomic patterns are associated…Distinct FDG PET Metabolic Signatures and Dopaminergic Loss Across Multiple System Atrophy Subtypes
Objective: To delineate subtype‑specific metabolic networks in Multiple system atrophy (MSA) using FDG‑PET, and to examine how these patterns relate to striatal dopamine transporter (DAT)…Phenoconversion from Rapid Eye Movement Sleep Behavior Disorder to Parkinson’s Disease: A multimodal Imaging Study
Objective: To elucidate the pathological progression from rapid eye movement sleep behavior disorder (RBD) to Parkinson’s disease (PD), we investigated tissue-level neurodegenerative changes using multimodal…Exchangeable copper as a monitoring tool in Wilson disease: lessons from a 24-month prospective cohort
Objective: To evaluate exchangeable copper (CuEXC) longitudinal kinetics and its association with clinical outcomes at 24 months in Wilson disease (WD). Background: CuEXC, reflecting the…Real-World Clinical Outcomes of Adaptive versus Continuous Deep Brain Stimulation in Early-Stage Parkinson’s Disease: A Systematic Review and Meta-Analysis of 2024-2025 Trials
Objective: To evaluate the comparative efficacy, safety, and energy efficiency of adaptive deep brain stimulation (aDBS) versus continuous deep brain stimulation (cDBS) in Parkinson’s disease…Effects of Dance for Parkinson’s on Disease Severity, Functional Mobility, and Habitual Physical Activity: A Feasibility Study
Objective: To examine the feasibility and effects of a Dance for Parkinson’s Disease® (DfPD®) intervention on disease severity, functional mobility, fine manual dexterity, and habitual…Clinical Outcomes and Safety of Ablative Surgery for Parkinson’s Disease in Resource-Limited Settings: A Cohort from Indonesia
Objective: To evaluate the clinical outcomes and safety of ablative surgery for Parkinson’s disease at Indonesia’s national tertiary referral neurological center. Background: Deep brain stimulation…Considering Oral Health to Optimise the Potential for Current and Future Treatments in Parkinson’s Disease
Objective: To determine if the Oral Health Assessment Questionnaire (OHAQ) devised by 2 Parkinson’s Disease Nurse Advanced Practitioners (PDNAP) could facilitate a healthier mouth to…
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