Sleep Patterns and Cognitive Function in Parkinson’s Disease: a Longitudinal Pilot Study
Objective: To evaluate the feasibility and usability of a commercially available wearable device for long-term monitoring of sleep patterns in Parkinson’s disease (PD) and how…Association of DAGLB Variants with Early-Onset Parkinson’s Disease Across Populations
Objective: Here, we investigated the contribution of DAGLB variants to PD across diverse ancestries using large-scale data from the Global Parkinson’s Genetics Program (GP2). Background:…A highly specific skin α-synuclein seed amplification assay for screening of synucleionpathies
Objective: To evaluate the performance of a skin α-synuclein seed amplification assay (skin_synSAA) as a screening test using samples from movement disorder subjects with uncertain…Validation of an Objective Parkinson’s Disease Digital Assessment Tool in Individuals with PD and Healthy Controls
Objective: To validate the sensitivity and accuracy of a video-based motor assessment platform (PRIMS) against a panel of expert MDS-UPDRS reviewers. Background: The platform is…Frequency-Specific Effects of SMA-rTMS on Gait Initiation in Parkinson’s Disease
Objective: To compare the effects of 25Hz (facilitatory) and 1Hz (inhibitory) repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) on gait initiation…Tremor on Smiling but Not Laughing: An Electrophysiological Study
Objective: This study aims to characterize the electrophysiological features of tremor during smiling, laughing, and smiling with vocalization. Background: Tremor on smiling, also referred to…Exploratory study of brain 5-HT4 receptor availability in early-stage Parkinson’s disease
Objective: To investigate possible alterations in the 5-HT4 serotonergic receptor in the brain of patients with PD at a relatively early stage, compared with healthy…Caudate-Predominant Striatal Dopaminergic Deficits in bvFTD with Parkinsonism
Objective: To characterize the dopaminergic lesion pattern in behavioral variant frontotemporal dementia with parkinsonism (bvFTD-P) using dopamine transporter (DAT) positron emission tomography (PET), and to…Functional Intramuscular Stimulation for Pain in Parkinson’s Disease and Sporadic Amyotrophic Lateral Sclerosis: A Retrospective Case Series
Objective: To describe clinical characteristics and short-term pain outcomes after functional intramuscular stimulation (FIMS) in patients with Parkinson's disease or sporadic amyotrophic lateral sclerosis. Background:…The Alternating Finger Tapping Test Poorly Predicts Real-World Daily Activity Performance in Parkinson’s Disease
Objective: To evaluate hand dexterity and daily hand task performance in individuals with PD and investigate the predictive validity of dexterity testing for functional impairment…
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