Efficacy of Bilateral Ventral Intermediate Nucleus Deep Brain Stimulation in Patients with Neuronal Intranuclear Inclusion Disease-Related Tremor: A Longitudinal Case Series
Objective: To investigate the therapeutic effect of deep brain stimulation (DBS) on patients with NIID-related tremor. Background: Neuronal intranuclear inclusion disease (NIID) is a rare,…Longitudinal cognitive trajectories and predictors of dementia conversion in Parkinson’s disease
Objective: To determine clinical predictors of longitudinal cognitive decline and dementia conversion in a real-world Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of…Expanding the Childhood Spectrum of Dentatorubral–pallidoluysian Atrophy: Neuropsychiatric and Motor Phenotypes in Four Siblings
Objective: We aim to characterize the striking clinical heterogeneity of movement, epileptic, and neuropsychiatric symptoms in a cohort of four siblings with genetically confirmed DRPLA.…Cross-Family Analysis of Rare Deleterious Variants Segregating in Families with Parkinson’s Disease
Objective: To identify potential novel variants and genes associated with Parkinson’s disease (PD) in multiplex families. Background: Identifying novel genes associated with PD is critical…A Digital Toolkit for Movement Disorders Clinicians
Objective: To evaluate early adoption and real-world usage patterns of a digital toolkit designed for movement disorders clinicians Background: Movement disorders clinicians rely on multiple…Automated MRI Biomarker Extraction for Parkinson’s Disease Using Attention-Based U-Net Segmentation
Objective: To evaluate a deep learning-based automated segmentation pipeline for extracting midbrain regions in MRI scans related to Parkinson’s disease. Background: Magnetic resonance imaging has…Interaction Between Physical and Cognitive Function That Determines ADL Improvement in Hospitalized Patients with Parkinson’s Disease: Implications for Individualized Rehabilitation Strategies
Objective: This study aimed to examine factors influencing the degree of improvement in the Barthel Index (BI) among hospitalized patients with PD and to clarify…Protocol for Rapidly Adaptive Deep Brain Stimulation to improve Freezing of Gait in Patients with Parkinson’s Disease
Objective: We aim to evaluate the effectiveness of single threshold adaptive deep brain stimulation (aDBS) for freezing of gait (FOG) in Parkinson’s disease (PD). We…Basal Ganglia Lacunar Infarcts and Risk of Mortality and Dementia in Parkinsonism: A Population-Based Study
Objective: To determine the prevalence of chronic basal ganglia lacunar infarcts (BGLI) and examine their association with dementia and mortality in a population-based cohort of…The Shape Of Sequence Effect In Parkinson’s Disease
Objective: The aim of this study is to objectively characterize and compare the temporal patterns of finger-tapping amplitude decrement in patients with Parkinson’s disease (PD)…
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