Safety and Effect of Ecopipam During the First 8 Weeks of Treatment for Tourette Syndrome: A Post Hoc Analysis
Objective: To assess the safety profile and effect of ecopipam, a selective dopamine D1 receptor antagonist, during the first 8 weeks of therapy for Tourette…Patient-centered Parkinson’s services and integrated primary care in southern Ghana: patient and caregiver perceptions from a cross-sectional survey
Objective: To evaluate patients’ and caregivers’ perceptions of patient-centered care for persons with Parkinson’s disease (PwPD) across three healthcare facilities in southern Ghana, and to…Neurophysiologic Testing Aids Diagnosis of Stiff-person Spectrum Disorders
Objective: To develop standardized, quantifiable criteria when using neurophysiologic techniques to diagnose SPSD. Furthermore, we desired two levels of diagnostic certainty: Neurophysiology Possible for high…Clinical and Psychophysiological Characteristics of Chronic Pain in Parkinson’s Disease: Pain Phenotypes, Central Sensitization, and Quality of Life
Objective: To assess clinical characteristics and pain phenotypes in PD patients with different types of chronic pain, to assess the severity of central sensitization and…Effects of Botulinum Toxin Therapy on Depression, Anxiety, Pain, and Quality of Life in Patients with Dystonia
Objective: To evaluate changes in depression,anxiety,pain, and quality of life alongside motor improvement in patients with dystonia treated with botulinum toxin(BoNT). Background: Dystonia is a…Gut Microbiome Metagenomics in Parkinson’s Disease Stratified by the Asian-Prevalent LRRK2 Variants p.G2385R and p.R1628P
Objective: To compare gut microbiome profiles of manifesting LRRK2 p.G2385R or p.R1628P carriers (LRRK2-PD) and idiopathic Parkinson’s disease patients (iPD). Background: Leucine-rich repeat kinase 2…Online Assessments Measure Motor and Cognitive Progression in People with and without Parkinson’s Disease
Objective: To evaluate longitudinal progression in online participant reported outcomes (PROs) among people with Parkinson’s disease (PD), prodromal PD, and healthy controls. Background: Collecting PROs…High-Frequency rTMS for Cognitive Impairment in Parkinson’s Disease: A Randomized Sham-Controlled Trial in Veterans
Objective: To evaluate the safety, feasibility, and potential cognitive effects of high-frequency rTMS targeting the left DLPFC in Veterans with PD-MCI. Background: Cognitive impairment is…Differential expression of nucleotide excision repair genes in Parkinson’s disease
Objective: To compare the relative expression of XPC, XPA, ERCC5, and ERCC4 between patients with Parkinson’s disease (PD) and controls. Background: DNA damage and impaired…Characteristics And Progression Of Non-Motor Symptoms In Parkinsons Disease
Objective: The aim of this study is to investigate the characteristics and the progression of different domains of NMS in PD, and to determine their…
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