Lead Asymmetry and Axial Symptom Response to Deep Brain Stimulation in Parkinson’s Disease: A Synthetic Pilot Modeling Study
Objective: To evaluate whether bilateral DBS lead placement asymmetry captures clinically meaningful correlates of motor outcomes, particularly freezing of gait (FoG) and balance to establish…Interest in Clinical Trial Participation in Parkinson’s Disease: Insights from a Nationwide Registry
Objective: To compare demographic, clinical, and socioeconomic characteristics of patients with Parkinson’s Disease (PD) who declared interest in participating in clinical trials with those who…Integrated Digital Monitoring and Outpatient Clinical Care Management Program for Parkinson Disease
Objective: Examine whether digital monitoring within Advanced Primary Care Management (APCM) can detect between-visit change, prompt care-plan updates, and streamline longitudinal management for medically complex…Digital Prediagnostic Mobility and Autonomic Trajectories in a Large Parkinson Disease Network
Objective: To evaluate whether digital mobility and autonomic trajectories detect prediagnostic decline beyond normative aging. Background: Identifying individuals in prodromal Parkinson disease who are nearing…Exploring Genetic Contributions to Disease Progression on Hoehn and Yahr Scales in Parkinson’s Disease
Objective: This study’s primary objective is to use Hoehn & Yahr (HY) staging to determine the genetic influence on motor progression through a longitudinal analysis…MLR–cerebellar network in body-first vs. brain-first PD: functional connectivity and clinical correlation with gait impairment
Objective: This study aims to clarify subtype-specific changes in mesencephalic locomotor region (MLR)-cerebellar functional connectivity(FC)[1][2] between body-first and brain-first Parkinson’s disease (PD) patients[3][4], and to further characterize…Dual-Site Transcranial Magnetic Stimulation Ameliorates Freezing of Gait in Parkinson’s Disease by Remodeling Cortical Excitatory-Inhibitory Balance and White Matter Microstructure: A Randomized Controlled Trial
Objective: To investigate whether dual-site [DS, primary motor cortex (M1) + supplementary motor area (SMA)] repetitive transcranial magnetic stimulation (rTMS) could attain superior efficacy compared…Exploring the Genetic Landscape of Corticobasal Syndrome in Asian Populations
Objective: We aimed to investigate the genetic spectrum of corticobasal syndrome (CBS) in a sizable Asian cohort. Background: CBS is a rare, rapidly progressive neurodegenerative…Explainable Machine-Learning Risk Stratification to Identify High-Potential Physical Therapy Responders with Freezing of Gait in Parkinson’s Disease
Objective: To develop an interpretable machine-learning model to predict freezing of gait (FOG) and identify Parkinson’s disease (PD) patients most likely to benefit from physical…Rehabilitation Practices in Parkinson’s Disease in Rome, Italy: Insights from Allied Health Professionals Priot to Implementation of the ParkinsonNet Model (ACTION-PD Project)
Objective: To investigate clinical experience, treatment practices, interprofessional collaboration among AHPs (allied health professionals) involved in people with Parkinson’s disease (PwP) care, prior to implementation…
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