MLR–cerebellar network in body-first vs. brain-first PD: functional connectivity and clinical correlation with gait impairment
Objective: This study aims to clarify subtype-specific changes in mesencephalic locomotor region (MLR)-cerebellar functional connectivity(FC)[1][2] between body-first and brain-first Parkinson’s disease (PD) patients[3][4], and to further characterize…Dual-Site Transcranial Magnetic Stimulation Ameliorates Freezing of Gait in Parkinson’s Disease by Remodeling Cortical Excitatory-Inhibitory Balance and White Matter Microstructure: A Randomized Controlled Trial
Objective: To investigate whether dual-site [DS, primary motor cortex (M1) + supplementary motor area (SMA)] repetitive transcranial magnetic stimulation (rTMS) could attain superior efficacy compared…Exploring the Genetic Landscape of Corticobasal Syndrome in Asian Populations
Objective: We aimed to investigate the genetic spectrum of corticobasal syndrome (CBS) in a sizable Asian cohort. Background: CBS is a rare, rapidly progressive neurodegenerative…Explainable Machine-Learning Risk Stratification to Identify High-Potential Physical Therapy Responders with Freezing of Gait in Parkinson’s Disease
Objective: To develop an interpretable machine-learning model to predict freezing of gait (FOG) and identify Parkinson’s disease (PD) patients most likely to benefit from physical…Rehabilitation Practices in Parkinson’s Disease in Rome, Italy: Insights from Allied Health Professionals Priot to Implementation of the ParkinsonNet Model (ACTION-PD Project)
Objective: To investigate clinical experience, treatment practices, interprofessional collaboration among AHPs (allied health professionals) involved in people with Parkinson’s disease (PwP) care, prior to implementation…Sleep habits and lifestyle factors in people with Parkinson’s disease compared with healthy controls
Objective: To evaluate the sleep habits and everyday lifestyle of Parkinson's disease (PD) patients compared to the healthy population. Background: Sleep disturbances are common non-motor…Improvement of Wearing‑Off Symptoms After Initiation of COMT Inhibitors in Parkinson’s Disease patients with early motor fluctuations: Results from the 12 months interim analysis of REONPARK Study
Objective: The REONPARK study is an observational study conducted in Spain aiming to evaluate COMT inhibitors (iCOMT) effectiveness and tolerability in alleviating motor complications associated…IMU Insole-Derived Gait Digital Biomarkers in idiopathic RBD and Parkinson Disease
Objective: To identify IMU insole-derived gait biomarkers differentiating healthy controls (HC), idiopathic rapid eye movement sleep behavior disorder (iRBD), and Parkinson disease (PD) during a…Randomized Controlled Trial Comparing Adaptive versus Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease; Closed Loop Optimization of Deep Brain Stimulation Effect in Parkinson’s Disease (CLOSE-PD study)
Objective: To evaluate whether adaptive deep brain stimulation (aDBS) of the subthalamic nucleus (STN) is more efficacious than continuous DBS (cDBS) in Parkinson's disease (PD)…Improving Equitable Access to Parkinson’s Disease Exercise Programs Through a Student-Led Transportation Model
Objective: To evaluate the feasibility and impact of a student-led transportation model designed to improve access to evidence-based exercise programs for people with Parkinson’s disease…
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