Role and significance of C-reactive protein in stages of Parkinson’s disease
Objective: To сomparative analysis of the amount of CRP in the blood serum of patients according to the stages of PD. Background: C-reactive protein (CRP)…The Transcriptomic, Neurotransmitter, and Cell Type Signatures Underlying Pure Fatigue in Early-stage Parkinson’s Disease
Objective: This study elucidates spatiotemporal functional connectivity of pure fatigue in early Parkinson’s disease (PD) and uncovering underlying gene expression profiles. Background: Fatigue is a…Sex-Specific Differences in Parkinson’s Disease: A Retrospective Analysis of over 10,000 Patients from the Paracelsus-Elena Hospital, a Specialized Movement Disorder Clinic in Germany
Objective: To analyze sex differences in PD in a large cohort from a hospital specializing in PD and other movement disorders. Background: Sex differences in…Movement Disorder Spectrum and Neurological Outcomes in Children with Neuronal Ceroid Lipofuscinosis
Objective: To describe the spectrum of movement disorders and associated clinical, genetic, and radiological features in children with Neuronal Ceroid Lipofuscinosis (NCL) Background: NCLs are…Impact of Multi-day Wearable Monitoring on Neurologists’ Assessment of Motor Fluctuations and Treatment Strategies in Parkinson’s Disease: A Real-World Study
Objective: To assess the impact of wearable-device objective metrics on neurologists’ perception and therapeutic decisions in a real-world cohort of patients with Parkinson’s disease (PD).…Power Spectral Density Increases Covary with Clinical Overstimulation During Dystonia Deep Brain Stimulation Programming
Objective: To assess the role of local field potential (LFP) as an acute biomarker of maximal tolerable stimulation (MTS) in dystonia patients. Background: Dystonia is…Levels of IgA and IgG concentrations by stage of Parkinson’s disease
Objective: To study of IgA and IgG levels cerebrospinal fluid of patients with different stages of PD. Background: In the clinical course of Parkinson's disease…RTN2 Variants Expand the ALS–Hereditary Spastic Paraplegia Disease Spectrum
Objective: To investigate the clinical and molecular characteristics of amyotrophic lateral sclerosis (ALS) families carrying variants in the RTN2 gene (SPG12), associated with hereditary spastic…Continuous Subcutaneous Levodopa Therapy Improves Motor Fluctuations and Quality of Life in Parkinson’s Disease: Evidence from Meta-analysis of Clinical Trials
Objective: To evaluate the efficacy and safety of subcutaneous levodopa/carbidopa or prodrug infusions in reducing OFF-time and improving quality of life in patients with Parkinson’s…Screening the Neuroprotective Potential of Mushroom Extracts in In Vitro Models of Parkinson’s Disease
Objective: This study aimed to evaluate the neuroprotective potential of various mushroom extracts across four distinct cellular models of PD. Furthermore, we sought to identify…
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