Serum Zinc Reduction During Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Parkinson’s Disease
Objective: To investigate whether continuous subcutaneous foslevodopa/foscarbidopa infusion reduces serum zinc levels in patients with Parkinson’s disease. Background: Reduced serum zinc levels in Parkinson’s disease…Structural Brain Measures Predict Cognitive Performance After Deep Brain Stimulation for Parkinson’s Disease
Objective: To determine whether pre-operative brain morphometry, combined with baseline neuropsychological performance, can predict post-operative cognitive performance in PD patients undergoing DBS using a sparse…Kinetic Features of Alpha-synuclein Positivity in CSF Seed Amplification in Parkinson’s Disease: an Exploratory Cross-cohort Analysis
Objective: To evaluate whether kinetic signatures from alpha-synuclein CSF seed amplification assays (aSynSAA) are generalizable among SAA-positive Parkinson’s Disease (PD) samples across previously published cohorts.…Impact of Helicobacter pylori Eradication on MDS-UPDRS Part III Motor Score in Patients With Parkinson’s Disease A Prospective Cohort Study in Northern Mexico
Objective: To determine the effect of Helicobacter pylori (H. pylori) eradication therapy on the Movement Disorder Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part III motor…Local Field Potential–Guided versus Clinically- Guided Electrode Identification For Continuous GPi -DBS in Parkinson’s Disease
Objective: To compare short-term motor, non-motor, and quality-of-life outcomes following LFP-guided versus clinically- guided electrode selection for cDBS of GPi in PD Background: Local field…Structural-Functional Coupling Supporting Motor Reserve in Early-Stage Parkinson’s Disease
Objective: To explore whether motor reserve in early Parkinson's disease (PD) is related to structural-functional coupling (SFC) Background: Motor reserve contributes to individual variability in…Elucidating the demographic distributions and implications of GBA1 gene variants in Parkinson’s Disease.
Objective: Estimating the distribution of GBA1 variants and estimating GBA1 odds ratios for Parkinson’s disease in the UK-based population. Background: Mutations in GBA1 are an…Environmental Risk Factor Co-Exposure as Drivers of Parkinson’s Disease Development: A Scoping Review
Objective: To map and synthesise epidemiological evidence assessing environmental co-exposures and Parkinson’s disease (PD) risk Background: PD is a multifactorial neurodegenerative disorder attributed to genetic,…Neural Network Reorganization Mediates the Analgesic Effects of Repetitive Transcranial Magnetic Stimulation in Parkinson’s Disease
Objective: To evaluate the efficacy of high-frequency M1-rTMS for musculoskeletal pain in PD and investigate its underlying neurophysiological mechanisms using multimodal electrophysiology and imaging. Background:…Clinical Profile and Progression of Parkinson’s Disease in Nigerians with the GBA1 African Ancestry-specific Risk Variant
Objective: This study compares clinical features and disease progression across rs3115534 genotypes (G/G, G/T, T/T) in Nigerians with Parkinson's disease (PD). Background: Variants in GBA1 are major…
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