Sleep disorder Clustering and Clinical Impact in Multiple System Atrophy
Objective: To characterize clustering patterns of sleep disorders in multiple system atrophy (MSA) and evaluate their clinical impact. Background: Sleep disorders are common in MSA.…Mirrored-Self Misidentification Expands the Neuropsychiatric Spectrum of Corticobasal Syndrome
Objective: To describe mirrored-self misidentification (MSM) occurring in corticobasal syndrome (CBS) without early dementia Background: CBS is a neurodegenerative syndrome characterized by asymmetric parkinsonism and…“Coder’s Cramp”: A Case Series of Task- Specific Typing Dystonia
Objective: We present a case series of task-specific dystonia that occurs exclusively when typing in three software engineers. Background: Task-specific dystonia refers to abnormal involuntary contraction of muscles only during a particular motor task. Focal hand dystonia related to one’s occupation can…A Retrospective Study Of Outcomes Of Deep Brain Stimulation In Juvenile Parkinson’s Disease.
Objective: To study the clinical characteristics of patients with JPD who have received DBS with their motor and psycho-social outcomes for a maximum of 5…Clinical and Multimodal Biomarker Profiles in Progressive Supranuclear Palsy: The PSPNI Cohort Study in China
Objective: To present an overview of the Progressive Supranuclear Palsy Neuroimage Initiative (PSPNI) from China. Background: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease…Prasinezumab’s Impact on Neuromelanin- and Iron-Sensitive MRI Biomarkers in Parkinson’s disease: Findings From the PADOVA Phase IIb Study
Objective: To evaluate the effects of prasinezumab on neuroimaging biomarkers in individuals with early-stage Parkinson’s disease (PD) on stable symptomatic medication. Background: PD is characterized by the…First-in-Human Single-Ascending-Dose Trial of ALN-SNCA, an Intrathecally Administered siRNA for Reducing α-synuclein, in Patients with Early-Stage Parkinson’s Disease
Objective: Development of a Phase 1, First-in-Human (FIH) clinical trial evaluating ALN-SNCA, a novel, intrathecally (IT) delivered small interfering RNA (siRNA) targeting SNCA mRNA to…Prevalence and neuroimaging presentations of Parkinsonism patients with p.R544C NOTCH3 mutation in Taiwan
Objective: To investigate the prevalence and neuroimaging findings of NOTCH3 p.R544C mutation in patients with Parkinsonism in Taiwan. Background: Cerebral autosomal dominant arteriopathy with subcortical…TRACK-PD: Understanding Treatment Routines and Adherence in Care – Knowledge and Perspective of People Living with Parkinson’s Disease
Objective: TRACK-PD aimed to assess adherence behaviors and drivers of treatment interruption/discontinuation from the patient perspective. Background: Treatment adherence is critical in Parkinson’s disease (PD),…Clinical Relevance of Oral Health Assessment in Parkinson’s Disease Monitoring
Objective: To evaluate the clinical relevance of oral health assessment in Parkinson’s disease (PD) by determining whether oral inflammatory, microbial, and periodontal alterations are associated…
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