Prevalence and associated factors of sarcopenia among Thai patients with ambulatory Parkinson’s disease
Objective: Objectives: To determine the prevalence of Asian Working Group for Sarcopenia (AWGS) 2019-defined sarcopenia phenotypes, identify associated factors, and evaluate screening performance in Thai PD patients. Background: Sarcopenia is…Exploring the Relationship Between Circadian Disruption, Depression and Suicidal Ideation in People with Huntington’s Disease (Mind & Clock Study)
Objective: To examine the relationship between circadian and sleep disruptions and depressive symptoms and suicidal ideation in people with Huntington’s Disease (PwHD) using scale-based and…Adaptive Subthalamic Nucleus Deep Brain Stimulation (aDBS) for Refractory Dyskinesia in Parkinson’s Disease: A Case Report of Two Patients
Objective: This is a case report of two patients to using adaptive subthalamic nucleus deep brain stimulation (aDBS) for refractory dyskinesia Background: Although continuous subthalamic…Semiquantitative [¹²³I]FP-CIT SPECT metrics combined with machine learning improve clinical differentiation of parkinson’s disease and atypical parkinsonian syndrome
Objective: To evaluate the capacity of semiquantitative striatal [¹²³I]FP-CIT SPECT-derived metrics to improve the clinical differentiation of degenerative parkinsonism through an integrated machine learning model.…Parkinson’s disease patients with sleep disturbances: Motor and non-motor profiling
Objective: To investigate whether sleep disturbances (SD) in Parkinson’s disease are associated with a distinct clinical profile in terms of motor and non-motor features. Background:…Clinical Features of Patients with an Essential Tremor–to–Parkinson’s Disease Diagnostic Trajectory
Objective: To characterize the clinical phenotype and disease course of patients with an ET-to-PD diagnostic trajectory in a tertiary-care setting. Background: The longitudinal clinical features…Remotely Administered Reaction Time Correlates in Progressive Supranuclear Palsy
Objective: To evaluate the cross-sectional associations of remotely administered reaction time (RT) in PSP. Background: PSP causes cognitive dysfunction, with severe deficits in psychomotor speed,…First Reported Experience of Dual Therapy With Deep Brain Stimulation and Foslevodopa/Foscarbidopa Subcutaneous Infusion
Objective: To describe the first evidence of dual therapy with deep brain stimulation (DBS) and foslevodopa/foscarbidopa (LDp/CDp) subcutaneous infusion treating Parkinson´s disease (PD). Background: In…One-Year Outcomes of Radiofrequency Thalamotomy Versus MR-Guided Focused Ultrasound: A Prospective Single-Centre Comparative Study
Objective: To prospectively compare 1 year clinical efficacy and safety following RF and MRgFUS thalamotomy in essential tremor. Background: Ventral intermediate nucleus (VIM) thalamotomy is…PPP2R2B Splice Variant Dysregulation Promotes Mitochondrial Association and Neuronal Apoptosis in iPSC-Derived Neurons from Spinocerebellar Ataxia Type 12 Patient
Objective: This study aimed to investigate the impact of PPP2R2B mutation in Spinocerebellar Ataxia Type 12 (SCA12) by analysing PPP2R2B splice variant expression, subcellular localization,…
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