Advancing Regular Non-motor Symptom Reporting During Inpatient Parkinson’s Disease Care Using a Self-Developed Digital Diary: A Three-Cohort Engagement Evaluation
Objective: To establish a robust digital approach that encourages hospitalized Parkinson’s disease (PD) patients to self-report non-motor symptoms throughout inpatient care, and to determine whether…Sleep Architecture and Cognitive Performance in Early Huntington’s Disease: A Pilot Study
Objective: Characterize sleep architecture and cognitive performance in people with early Huntington’s disease (HD) and explore their associations. Background: Cognitive impairment is a devastating feature…Challenges of Translating the MDS-UPDRS into Ukrainian During Wartime
Objective: To describe the practical, linguistic, and logistical challenges encountered during the Ukrainian translation and cultural adaptation of the MDS-UPDRS. Background: The process of translating…Emergence of Cortical Amyloid from the Prodromal Stage of the Lewy Body Disease Spectrum: Evidence from a PiB-PET Study
Objective: To characterize β-amyloid (Aβ) deposition across the Lewy body disease (LBD) spectrum using Pittsburgh compound B positron emission tomography (PiB-PET) and examine the influence…Physiotherapists’ Clinical Reasoning When Selecting Compensatory Strategies for Gait Impairments in Parkinson’s Disease
Objective: To examine physiotherapists’ understanding of compensatory strategies and how they select them for gait impairments in people with Parkinson’s disease (PwP). Background: Compensatory strategies…Mechanical Ventilation Modifies the Natural History of DCTN1 p.G71A Perry Disease: A 20-Year Longitudinal Study
Objective: To determine whether mechanical ventilation modifies survival and disease trajectory in an expanded Japanese pedigree with DCTN1 p.G71A–related Perry disease. Background: Perry disease is…Structural-Functional Decoupling and Imaging Transcriptomics in Cognitive Impairment of Parkinson’s Disease
Objective: To examine SDI across cognitive stages of Parkinson’s disease (PD) and its associations with cortical thickness (CTh), cognition, and cell-type transcriptomic signatures. Background: Cognitive…Impact of Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion on Neuropsychiatric Symptoms in Clinical Practice: A Multicenter Study
Objective: To determine the incidence and risk factors of neuropsychiatric adverse events (AEs) in patients with Parkinson’s disease (PD) treated with foslevodopa/foscarbidopa continuous subcutaneous infusion…DCTN1 Gene: A p.(Gly59Ser) Family Report
Objective: Describing two patients from an Italian family carrying the DCTN1 p.(Gly59Ser) and their phenotypes. Background: Mutations in Dynactin 1 (DCTN1) gene are responsible for…Clinical and Genetic Profile of the ACTIVATE Population: A Phase 2 Trial of BIA 28-6156 in GBA-PD
Objective: To characterize the patient population enrolled in the ACTIVATE study, a Phase 2 multicenter, randomized, double-blind, placebo-controlled trial assessing the efficacy, safety, tolerability, pharmacodynamics,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.