MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2026 International Congress

    Cerebrospinal Fluid Markers are associated with Cognitive Decline in GBA1-associated Parkinson’s Disease

    M. Bode, C. Schulte, S. Becker, I. Wurster, B. Roeben, S. Lerche, W. Poewe, K. Brockmann, I. Liepelt-Scarfone (Tübingen, Germany)

    Objective: To analyze whether and how cerebrospinal fluid (CSF) amyloid-related markers relate to the longitudinal cognitive profile in PD-GBA1. Background: Cognitive decline in Parkinson’s disease…
  • 2026 International Congress

    Does Fall-Related Activity Avoidance Differ between people with Parkinson’s disease versus Cognitively Unimpaired Controls?

    M. Lindh-Rengifo, E. Franzén, M. Landers, E. Stomrud, M. Nilsson (Malmö, Sweden)

    Objective: investigate whether fall-related activity avoidance differs between people with Parkinson’s disease (PD) versus cognitively unimpaired controls (CU) without any significant neurological disease. Background: Although…
  • 2026 International Congress

    Development and preliminary results of a new self-assessment tool for neuropsychiatric syndromes in Parkinson’s Disease

    U. Lambotte, C. Schedlich-Teufer, S. Simon, A. Sauerbier, JC. Baldermann-Weiß, L. Hesse, D. Gruber, G. Ebersbach, W. Jost, E. Kalbe, GR. Fink, J. Kessler, MT. Barbe, SJ. Jost (Cologne, Germany)

    Objective: To develop a self-report screening tool for neuropsychiatric syndromes (NPS) in patients with Parkinson’s Disease (PD) and to conduct an initial evaluation of its…
  • 2026 International Congress

    Stakeholder Engagement to Inform Research on Suicidality and Assisted Dying in Parkinson’s

    L. Wright, S. Hussain-Ali, A. Noyce, L. Smith (London, United Kingdom)

    Objective: To explore stakeholder perspectives to identify shared research priorities on suicidality and assisted dying in Parkinson’s and co-design subsequent research. Background: People with Parkinson’s…
  • 2026 International Congress

    When Presynaptic Stimulation is Not Enough: Severe Biphasic Dyskinesia on LECIG Reversed by Postsynaptic Apomorphine Rescue

    A. Alonso Cánovas, I. Parees Moreno, C. Moreno Lopez, A. Patiño Paton, EJ. Martinez Esteban, P. Perez Torre, JL. López Sendón, JC. Martinez Castrillo (Madrid, Spain)

    Objective: To report an exceptional case of advanced Parkinson’s disease (PD) where levodopa/carbidopa/entacapone intestinal gel (LECIG) failed to provide adequate motor control, ultimately requiring a…
  • 2026 International Congress

    Single stage Dual target Deep Brain Stimulation for Dystonic Tremor

    T. Maiti, C. Ugas, S. Mittal (Abu Dhabi, United Arab Emirates)

    Objective: Choosing the right target for deep brain stimulation surgery for dystonic tremor can be tricky. Patients usually treated by VIM-DBS or GPi-DBS.  Dual targeting is…
  • 2026 International Congress

    Midbrain Organoid Modeling and Transcriptomic Characterization of NOTCH2NLC GGC Repeat Expansion–Associated Parkinson’s Disease

    H. Qian, Y. Chen, W. Wei (Hangzhou, China)

    Objective: To characterize transcriptomic alterations in patient-derived midbrain organoids carrying NOTCH2NLC GGC repeat expansions and assess their relevance to canonical Parkinson's disease (PD) mechanisms. Background:…
  • 2026 International Congress

    The Dual Functional Organization of the Substantia Nigra in Parkinson’s Disease

    M. Passaretti, D. Vereb, B. Zufiria-Gerbolés, M. Mijalkov, M. Veronese, J B. Pereira (Stockholm, Sweden)

    Objective: We applied connectopic mapping to the internal functional organisation of the substantia nigra (SN) in independent cohorts. Background: The human SN is a central…
  • 2026 International Congress

    A Novel Therapeutic Targeting the tPA-NMDAr Interaction for Multiple System Atrophy

    N. Delétage, F. Lesept, A. Henriques, N. Callizot, E. Bezard, M. Blanc (Lyon & Caen, France)

    Objective: LYS241, a first-in-class, humanized, and optimized monoclonal antibody, designed to inhibit the interaction between tissue plasminogen activator (tPA) and N-methyl-D-aspartate receptor (NMDAr), has demonstrated…
  • 2026 International Congress

    Validation of the Chinese Version of the Unified Multiple System Atrophy Rating Scale

    AK. Berger, A. Rieckmann, D. Oudin ǻström, S. Zanigni, Q. Zhou, T. Feng, H. Wang, J. Wang, B. Tang, CF. Liu, H. Chen, W. Mao, P. Chan, H. Shang, L. Cui (Valby, Denmark)

    Objective: To assess the psychometric properties of the Chinese version of the Unified Multiple System Atrophy Rating Scale (UMSARS). Background: The UMSARS is the gold‑standard…
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