Clinical and Programming Parameter Comparison of STN and GPi Deep Brain Stimulation Targets in Parkinson’s Disease
Objective: To compare subthalamic nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation targets in Parkinson’s disease (PD) regarding demographic characteristics, preoperative cognitive profile,…Machine Learning-Based Frequency-Domain Analysis of Gait Acceleration for Huntington’s Disease Detection
Objective: To investigate the diagnostic utility of machine learning-driven frequency-domain analysis of gait acceleration for the objective identification of Huntington’s Disease (HD). Background: Gait disturbances…Congenital Portosystemic Shunting: A Wilson’s Disease Mimic
Objective: To report a patient with a congenital extrahepatic portosystemic shunt with features mimicking those seen in Wilson’s disease Background: Wilson’s disease is an autosomal recessive disorder caused by…From Down Under to a Global Audience: Engaging 25,000 People Across 160 Countries to Improve Parkinson’s Knowledge and Awareness
Objective: We aimed to develop a freely accessible massive open online course (MOOC) on Parkinson’s disease, including modules addressing symptoms, diagnosis, underlying biology, medical management,…Social Cognition in Patients with Parkinson’s Disease
Objective: We aimed to investigate social cognition in patients with Parkinson's disease (PD) using facial affect tasks of the Florida Affect Battery (FAB). Background: Patients with…DJ-1 (PARK7) Heterozygous Mutation and Early-Onset Parkinson’s Disease: A Chilean Case Report and Literature Review
Objective: We report a Chilean patient with childhood-onset Parkinson’s disease (PD) carrying a single heterozygous PARK7 (DJ-1) mutation and review its clinical and pathophysiological relevance.…Development of a Parkinson’s Disease Dyadic Multidisciplinary Illness Management Program: Protocol for PATH Parkinson
Objective: This study describes the development of partnership-based assistive team-based healing (PATH) Parkinson, a chatbot-based multidisciplinary mobile application (app) designed for patient–caregiver dyads with Parkinson’s…Evaluating pseudo-monopolar LFP recordings from the STN for optimized DBS contact selection in Parkinson’s disease
Objective: To evaluate the utility of pseudo-monopolar local field potential (LFP) recordings using Electrode Identifier (EI; automated contact-ranking algorithm) for contact selection in STN-DBS, compared…Personalized Rhythmic Cueing Differentially Improves Straight Walking and Turning in Parkinson’s Disease
Objective: To evaluate the effects of different rhythmic auditory stimulation (RAS) strategies on straight walking and turning in Parkinson’s disease (PD) and identify clinical predictors…Early Overlap of Corticobasal Syndrome and Richardson Syndrome in Corticobasal Degeneration: Evidence from 252 Autopsy-Confirmed Cases
Objective: This study aimed to identify early clinical phenotypes of corticobasal degeneration (CBD) using unsupervised analysis of a large clinicopathologic dataset. Background: Early diagnosis of…
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