“Step-by-Step” in Movement Disorders: A Disease-Specific, Multi-Method Integrated Teaching Approach
Objective: To evaluate the effectiveness of a novel “Step-by-Step” teaching round model in improving neurology residents’ knowledge and clinical competency in movement disorders. Background: Movement…Phenotypic and Genotypic Spectrum of MAPT-associated Parkinsonism in a Multi-ethnic Malaysian Cohort
Objective: To describe the phenotypic continuum and genotypic spectrum of microtubule-associated protein tau (MAPT)-associated parkinsonism in a multi-ethnic Malaysian cohort. Background: Carriers of pathogenic MAPT…Urine-derived neuronal extracellular vesicle α-synuclein seed amplification assay for synucleinopathies: a non-invasive biomarker study
Objective: To investigate whether pathogenic α-synuclein can be detected using real-time quaking-induced conversion (RT-QuIC) in urine-derived neuronal extracellular vesicles (NEVs) as a fully non-invasive biomarker…Brain-Derived Neurotrophic Factor as a Biomarker of Depression in Parkinson’s Disease
Objective: To determine whether peripheral neurodegeneration-related biomarker levels differ between patients with Parkinson’s disease (PD) with and without depression and to identify biomarkers associated with…Clinical and Functional Outcomes of Antiviral and Immunomodulatory Therapies in Subacute Sclerosing Panencephalitis
Objective: To evaluate whether antiviral and immunomodulatory treatments meaningfully improve true functional status and disease stabilization, or if they merely prolong survival in a state…Botulinum toxin treatment patterns and outcomes in head and neck dystonia: experience from a tertiary, multidisciplinary clinical service
Objective: To evaluate outcomes following Botulinum toxin (BoNT) treatment for head and neck dystonia in a tertiary multidisciplinary clinic, characterise adverse effects and identify treatment…Immunological principles of levodopa therapy in Parkinson’s disease
Objective: Study of the relationship between serum IL-10 levels in patients with Parkinson's disease and levodopa therapy Background: In Parkinson's disease, dehydroepiandrosterone can lead to…Spectrum of Orthopaedic Problems in Patients with Movement Disorders: A Systematic Review of Clinical Manifestations
Objective: To identify and summarizes the spectrum of orthopedic problems reported in patients with movement disorders Background: Movement disorders such as Parkinson's disease, Dystonia, Essential tremor,…Interleukin 6 in the assessment of Parkinson’s disease and Progressive Supranuclear Palsy
Objective: The aim of this research is to analyze the relevance of serum interleukin 6 levels in the evaluation of Parkinson’s disease (PD) and Progressive…Point-of-Care Neuromuscular Ultrasound With Fractal Biomarkers for Stratification of Neuropathic and Myogenic Drivers of Motor Decline
Objective: We investigated whether a structured ultrasound protocol integrating fascicular morphometry, fractal image analysis, and AI-assisted classification can stratify neuropathic versus myogenic contributors to motor…
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