International, multicenter validation study of the Shame in Parkinson’s disease (SPARK) Scale
Objective: To evaluate the psychometric properties of the Shame in PARKinson’s disease (SPARK) Scale in Parkinson’s disease patients, using both classical test theory (CTT) and…Healthcare Resource Utilization and Associated Costs in Adults with Isolated Dystonia in the United States
Objective: To evaluate all-cause healthcare resource utilization (HCRU) and costs in adults with isolated dystonia in the United States. Background: Isolated dystonia is a rare,…Functional Movement Disorders in Older Adults in Latin America: A Narrative Literature Review
Objective: To review the available literature on FMD in older adults (aged ≥ 65 years) in Latin America, focusing on epidemiology, clinical features, diagnostic challenges, treatment, and…Clinician Guided Multimodal Kinematic AI System for Objective Assessment in Parkinson’s Disease
Objective: To evaluate the feasibility of developing a novel Multimodal Kinematic Artificial Intelligence (MKAI) system, uniquely guided by expert physician evaluation notes, to generate objective,…Identification of Alpha-synuclein Pathology in Dementia with Lewy Body Participants by Seed Amplification Assay
Objective: To assess frequency and type of misfolded α-synuclein aggregates (syn-seeds) in cerebrospinal fluid (CSF) from dementia with Lewy bodies (DLB) participants by means of…Reducing Cost and Operative Time in DBS with a Consolidated Workflow: A Time-Driven Activity-Based Costing Analysis
Objective: To show that a consolidated patient specific workflow significantly improved operative efficiency and reduced personnel costs for deep brain stimulation (DBS) implantation, without compromise…Longitudinal motor network responses to pallidal DBS in cervical dystonia: an ongoing DBS-fMRI study
Objective: This longitudinal MRI study in cervical dystonia uses functional MRI (fMRI) to evaluate neural mechanisms underlying clinical response to deep brain stimulation (DBS), with…Social Determinants of Health and MSA survival
Objective: To investigate how social determinants of health affect survival in people with Multiple System Atrophy Background: The wider determinants of health (e.g. socioeconomic and…The Lewy Body Dementia Domain Rating Scale (LBD-DRS): Patient and Care Partner Perspectives
Objective: To develop and validate the Lewy Body Dementia Domain Rating Scale (LBD-DRS), a disease-specific outcome measure designed to comprehensively capture the clinical features and…MT200605 for Huntington’s Disease: Nonclinical finding and Phase I Clinical Result
Objective: To summarize the efficacy of the oral MT200605 formulation in a Huntington’s disease (HD) mouse model and current clinical progress of MT200605. Background: MT200605…
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