The influence of Parkinson’s disease duration on perceived quality of inpatient care
Objective: There are currently no disease-modifying therapies for persons with Parkinson’s disease (PD), and progressive symptoms contribute to increased risk of hospitalization, particularly in the…Handwriting Based Screening of Parkinson’s Disease Using Image Analysis of Drawing Tasks
Objective: To evaluate whether image-based analysis of handwriting drawing tasks can distinguish Parkinson's disease from healthy controls. Background: Fine motor impairment is a core feature…Evidence of Systemic and Neuro-Inflammation in Progressive Supranuclear Palsy: Insight from an Imaging-Inflammation Study
Objective: To investigate the role of Th17 pathway in systemic and central inflammation in PSP and to identify signatures of inflammation-induced neurodegeneration in PSP. Background:…Grip strength and hand distress in de novo Parkinson´s disease: support for early rehabilitation
Objective: To describe grip strength and upper limb (UL) distress in de novo PD, and to explore associations with motor symptoms. Background: Grip strength is…Incidence and movement disorders associated with Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in the Princess Maha Chakri Sirindhorn Medical Center (MSMC)
Objective: To identify incidence and clinical features of SREAT patients in MSMC. Background: SREAT patients could present with encephalopathy with various neurological abnormalities, including behavioral…A Longitudinal Case of Adult-Onset Progressive Ataxia in a Patient with a Pathogenic Variant of IRF2BPL
Objective: To describe the course of a patient with an inherited IRF2BPL variant presenting as adult-onset indolent ataxia and tremor with no prior developmental abnormalities,…Unnecessary Ablative Surgery in an Untreated Parkinson’s Disease Patient: Marked Clinical Improvement After Initiation of Dopaminergic Therapy
Objective: To report a case of Parkinson’s disease (PD) in which two ablative procedures were performed without prior dopaminergic therapy, followed by significant clinical improvement…Irisin as a Molecular Mediator of Exercise Induced Neuroprotection and Disease Modification in Parkinson’s Disease
Objective: To integrate mechanistic evidence delineating irisin mediated molecular pathways relevant to Parkinson’s disease (PD) pathogenesis and neuroprotection, focusing on α-syn clearance, autophagy–lysosomal function, mitochondrial…Cross-Cultural Validation of the Hebrew version of The International Parkinson and Movement Disorder Society Non-Motor Rating Scale
Objective: This study aims to validate the Hebrew version of the MDS-NMS and make it suitable for use in Hebrew speaking population Background: Parkinson's disease is a complex neurodegenerative disease with…Comparative efficacy and safety of Safinamide versus Opicapone in Japanese patients with Parkinson’s Disease and wearing-off: A matching-adjusted indirect comparison
Objective: To compare efficacy and safety outcomes with safinamide and opicapone as adjuncts to levodopa in Parkinson’s disease (PD) patients with wearing-off using an anchored…
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