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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2019 International Congress » Gene and Cell-Based Therapies

Date: Monday, September 23, 2019

Time: 1:45pm-3:15pm

Location: Les Muses Terrace, Level 3

Meeting: 2019 International Congress

1:45pm-3:15pm
Bilateral Putaminal AAV2-GDNF Delivery the Treatment of Advanced Parkinson’s Disease

K. Bankiewicz, C. Lungu, D. Hammoud, P. Herscovitch, D. Ehrlich, D. Argersinger, S. Sinharay, G. Scott, T. Wu, W. San Sebastian, V. Suhakar, M. Fiandaca, K. Zaghloul, M. Hallett, R. Lonser, J. Heiss (San Francisco, CA, USA)

1:45pm-3:15pm
Differential effects of stem cell therapy in adult and middle-aged Parkinsonian mice

A. Nelke, S. García-López, A. Martínez-Serrano, M. Pérez Pereira (Madrid, Spain)

1:45pm-3:15pm
Disease-in-a-dish: drug discovery using patient-derived stem cells in Hereditary Spastic Paraplegia

Y. Fan, G. Wali, R. Sutharsan, C. Sue, A. Mackay-Sim (Sydney, Australia)

1:45pm-3:15pm
Evidence of survival and integration of implanted autologous peripheral nerve graft in substantia nigra in a patient with Parkinson’s disease

DR. Ginjupally, G. Quintero, Z. Guduru, J. Gurwell, J. Slevin, A. Granholm, G. Gerhardt, C. van Horne (Denver, CO, USA)

1:45pm-3:15pm
Increased level of a lysosomal phospholipid, BMP, in urine of LRRK2 G2019S mutation carriers with or without Parkinson’s disease: implications for therapeutic development

R. Alcalay, F. Hsieh, S. Padmanabhan, M. Baptista, C. Kehow, S. Narayan, A. Boehme, K. Merchant (Cambridge, MA, USA)

1:45pm-3:15pm
Investigating the impact of a-synuclein pathology on human embryonic stem cell derived dopaminergic neurons transplanted in an accelerated a-synuclein rat model of Parkinson’s disease

D. Hoban, S. Shrigley, L. Breger, J. Nelander Wahlestedt, T. Cardoso, B. Mattsson, K. Luk, M. Parmar, A. Björklund (Lund, Sweden)

1:45pm-3:15pm
Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01

A. van Laar, R. Richardson, A. Sedkov, E. Fine, K. Bankiewicz, B. Ravina, P. Larson, C. Christine (Pittsburgh, PA, USA)

1:45pm-3:15pm
Neuritic pathology in Parkinson’s Disease results from loss of anti-oxidant response activity

S. Ryan, M. Stykel, C. Coackley, T. Ryan (Guelph, ON, Canada)

1:45pm-3:15pm
Restoring AADC enzyme synthesis in AADC deficiency: MRI-Guided Delivery of AAV2-hAADC Gene Therapy to the Midbrain

K. Bankiewicz, T. Pearson, A. Grijalvo-Perez, A. Viehoever, W. San Sebastian, J. Imamura-Ching, Y. Seo, P. Larson, N. Gupta (San Francisco, CA, USA)

1:45pm-3:15pm
Texas Biorepository of Human Induced Pluripotent Stem Cells for Studying Parkinson’s Disease

S. Wijemanne, H. Hong, G. Choudhury, J. Kim, J. Ramirez-Castaneda, A. Papanastassiou, M. Daadi (San Antonio, TX, USA)

1:45pm-3:15pm
TFEB-driven expression prevents neurodegeneration in a multiple system atrophy mouse model

ML. Arotcarena, M. Bourdenx, N. Dutheil, ML. Thiolat, E. Doudnikoff, S. Dovero, A. Ballabio, PO. Fernagut, W. Meissner, E. Bezard, B. Dehay (Bordeaux, France)

1:45pm-3:15pm
The Role of Dysfunctional BDNF in Remodeling the Parkinsonian Striatum Following Dopamine Neuron Grafting in CRISPR rs6265 Rats

N. Mercado, J. Stancati, T. Collier, C. Sortwell, I. Sandoval, C. Kemp, B. Daley, M. Duffy, K. Steece-Collier (Grand Rapids, MI, USA)

« View all sessions from the 2019 International Congress.

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