2019 International Congress » Gene and Cell-Based Therapies

Date: Monday, September 23, 2019

Time: 1:45pm-3:15pm

Location: Les Muses Terrace, Level 3

Meeting: 2019 International Congress

1:45pm-3:15pm: Bilateral Putaminal AAV2-GDNF Delivery the Treatment of Advanced Parkinson’s Disease

K. Bankiewicz, C. Lungu, D. Hammoud, P. Herscovitch, D. Ehrlich, D. Argersinger, S. Sinharay, G. Scott, T. Wu, W. San Sebastian, V. Suhakar, M. Fiandaca, K. Zaghloul, M. Hallett, R. Lonser, J. Heiss (San Francisco, CA, USA)

1:45pm-3:15pm: Differential effects of stem cell therapy in adult and middle-aged Parkinsonian mice

A. Nelke, S. García-López, A. Martínez-Serrano, M. Pérez Pereira (Madrid, Spain)

1:45pm-3:15pm: Disease-in-a-dish: drug discovery using patient-derived stem cells in Hereditary Spastic Paraplegia

Y. Fan, G. Wali, R. Sutharsan, C. Sue, A. Mackay-Sim (Sydney, Australia)

1:45pm-3:15pm: Evidence of survival and integration of implanted autologous peripheral nerve graft in substantia nigra in a patient with Parkinson’s disease

DR. Ginjupally, G. Quintero, Z. Guduru, J. Gurwell, J. Slevin, A. Granholm, G. Gerhardt, C. van Horne (Denver, CO, USA)

1:45pm-3:15pm: Increased level of a lysosomal phospholipid, BMP, in urine of LRRK2 G2019S mutation carriers with or without Parkinson’s disease: implications for therapeutic development

R. Alcalay, F. Hsieh, S. Padmanabhan, M. Baptista, C. Kehow, S. Narayan, A. Boehme, K. Merchant (Cambridge, MA, USA)

1:45pm-3:15pm: Investigating the impact of a-synuclein pathology on human embryonic stem cell derived dopaminergic neurons transplanted in an accelerated a-synuclein rat model of Parkinson’s disease

D. Hoban, S. Shrigley, L. Breger, J. Nelander Wahlestedt, T. Cardoso, B. Mattsson, K. Luk, M. Parmar, A. Björklund (Lund, Sweden)

1:45pm-3:15pm: Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01

A. van Laar, R. Richardson, A. Sedkov, E. Fine, K. Bankiewicz, B. Ravina, P. Larson, C. Christine (Pittsburgh, PA, USA)

1:45pm-3:15pm: Neuritic pathology in Parkinson’s Disease results from loss of anti-oxidant response activity

S. Ryan, M. Stykel, C. Coackley, T. Ryan (Guelph, ON, Canada)

1:45pm-3:15pm: Restoring AADC enzyme synthesis in AADC deficiency: MRI-Guided Delivery of AAV2-hAADC Gene Therapy to the Midbrain

K. Bankiewicz, T. Pearson, A. Grijalvo-Perez, A. Viehoever, W. San Sebastian, J. Imamura-Ching, Y. Seo, P. Larson, N. Gupta (San Francisco, CA, USA)

1:45pm-3:15pm: Texas Biorepository of Human Induced Pluripotent Stem Cells for Studying Parkinson’s Disease

S. Wijemanne, H. Hong, G. Choudhury, J. Kim, J. Ramirez-Castaneda, A. Papanastassiou, M. Daadi (San Antonio, TX, USA)

1:45pm-3:15pm: TFEB-driven expression prevents neurodegeneration in a multiple system atrophy mouse model

ML. Arotcarena, M. Bourdenx, N. Dutheil, ML. Thiolat, E. Doudnikoff, S. Dovero, A. Ballabio, PO. Fernagut, W. Meissner, E. Bezard, B. Dehay (Bordeaux, France)

1:45pm-3:15pm: The Role of Dysfunctional BDNF in Remodeling the Parkinsonian Striatum Following Dopamine Neuron Grafting in CRISPR rs6265 Rats

N. Mercado, J. Stancati, T. Collier, C. Sortwell, I. Sandoval, C. Kemp, B. Daley, M. Duffy, K. Steece-Collier (Grand Rapids, MI, USA)

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