Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…Antihypertensive medications have protective associations with PD outcomes in PD-hypertension
Objective: We explored the associations between markers of clinical decline and antihypertensive use in subjects with both Parkinson disease (PD) and hypertension (HTN) Background: Comorbid…Life Expectancy for Parkinson Patients at Hoehn and Yahr Stage 5
Objective: this study was carried out to analyze the average time taken for parkinson patients to progress from HY stage 5 to death, and investigate…Preliminary evaluation of the Integrated Parkinson’s Care Network (IPCN): An integrated care model for complex needs
Objective: To conduct a preliminary evaluation of the IPCN for: 1) proof of concept, 2) processes refinement for its evaluation, and 3) assess the feasibility…Instrumented gait analysis identifies potential predictors for Parkinson’s disease converters
Objective: This longitudinal prospective observational study investigated if gait can predict Parkinson’s disease (PD) conversion from a cohort of community-dwelling older adults. Background: PD is…Arm swing asymmetry in Parkinson Disease patients using a portable RGBD camera
Objective: To describe the differences in arm swing asymmetry between patients with PD and a healthy subjects group using portable RGBD camera. Background: Changes in…A study on pre-adoption of a self-management application by Parkinson’s disease patients
Objective: The aim of this paper is to investigate factors influencing acceptance by Parkinson's disease (PD) patients of a self-management application for an Internet of…Adult neurogenesis is impaired in pink1-/- zebrafish (Danio rerio)
Objective: To determine whether PINK1 deficiency impairs adult neurogenesis in a tractable vertebrate model of PINK1-related Parkinson's disease (PD). Background: PD is characterized by loss…Loss of VPS29 disrupts retromer function and synaptic transmission, leading to neurodegeneration in Drosophila
Objective: To understand the role of the retromer complex in the central nervous system(CNS), and its link to Parkinson's disease (PD) susceptibility. Background: Mutations in…Analyses of physical activity on cognitive flexibility, depression and RBD in healthy elderly with high risk for neurodegenerative diseases
Objective: In this study we set out to evaluate the effect of physical activity on cognition, fine motor movements and axial motor parameters in a…
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