Impact of Innovative Physiotherapy Interventions on Motor Function and Quality of Life in Patients with Parkinson’s Disease and Movement Disorders
Objective: 1. Assess the extent to which innovative physiotherapy interventions improve motor function, as measured by the Unified Parkinson’s Disease Rating Scale (UPDRS).2. Determine the…Breaking Away From the Ivory Tower
Objective: We describe the evolution of the Geriatric Flying Squad (GFS), a rapid response outreach team for residential aged care facilities (RACFs) in the local…A Long-Living Human Tissue Engineered Nigrostriatal Pathway as a Testbed to Study Parkinson’s Disease
Objective: To create a three dimensional (3D) long-living model of human tissue-engineered nigrostriatal pathway (TE-NSP) comprised of discrete somatic and axonal compartments recapitulating the native…Detection and characterization of rare variants in NOTCH2NLC causing false negative molecular diagnosis through long-read sequencing
Objective: This study investigated a NIID patient with typical clinical and imaging features but no detectable NOTCH2NLC GGC expansion using standard testing. Whole-genome long-read sequencing…Semantic Memory Deficit as a Potential Risk Factor of Dementia in Isolated Rapid Eye Movement Sleep Behavior Disorder
Objective: We aimed to evaluate semantic memory (SM) performance in isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) and identify the specific profile of…Diagnostic and Treatment Delays in Normal Pressure Hydrocephalus: A Retrospective Analysis at a Tertiary Care Center
Objective: To identify and evaluate critical points of delay in the diagnosis and treatment of normal pressure hydrocephalus (NPH) at a tertiary care center. Background:…Bidirectional Relationships Between Frailty and DNAm Age Acceleration and its Mediation Effects on Physical Disability and Mortality
Objective: This study aims to investigate the bidirectional associations between frailty and DNA methylation (DNAm) age acceleration (AgeAccel), and further test whether epigenetic aging mediates…Transformation of Parkinson’s care through Self-Management, Remote monitoring and Timely review (SMaRT-PD): Care Pathway Mapping with Clinical Experts
Objective: To elicit healthcare professionals’ perspectives on the introduction of a clinical decision support system (CDSS) to facilitate Parkinson’s disease care provision: impact on current…Age- and Sex-Associated Changes in the Behavior of Neuronal Mitochondria During Healthy Aging
Objective: To determine age-associated changes in the size, density, movement, and dynamics of mitochondria as a function of sex, using microRNA-induced neurons derived from primary…Cortical activity during visually perturbed gait in older adults
Objective: The primary aim of this preliminary study was to explore pre-frontal cortex (PFC) and posterior parietal cortex (PPC) activity in older adults (OAs) during…
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