Functional Movement Disorders in Older Adults in Latin America: A Narrative Literature Review
Objective: To review the available literature on FMD in older adults (aged ≥ 65 years) in Latin America, focusing on epidemiology, clinical features, diagnostic challenges, treatment, and…Chronic Vanadium Exposure Promotes Memory Impairment and Aggregation of Alpha-Synuclein, Tau and Amyloid Beta in Mouse Brain
Objective: In this study, we hypothesized that prolonged vanadium exposure may be a potential risk factor for Alzheimer's and Parkinson's diseases. Background: The interaction between…Prevalence of Parkinson’s Disease in the South Tongu District of Ghana and Projections of Current and Future Disease Burden (2026 – 2040)
Objective: To determine the prevalence of Parkinson’s disease (PD) in Ghana, West Africa. Background: PD is the fastest-growing neurological disorder and a leading cause of…Effects of Personalized Visual and Auditory Cueing on Sit-to-Stand Biomechanics in Individuals with Parkinson’s disease: A Subgroup Analysis
Objective: To investigate the effects of personalized visual and auditory cueing combined with task-specific sit-to-stand training on movement kinematics, functional mobility, and psychosocial outcomes in…Segment-Level Gait Dynamics Reveal Parkinsonian Motor Signatures in Fall-Prone Older Adults Using Multi-Channel Time–Frequency Deep Learning
Objective: To develop a multi-channel time–frequency deep learning framework capable of identifying Parkinsonian gait dynamics from short locomotor segments and detecting PD-like motor state transitions…Machine Learning–Based Brain Age Modeling Reveals Accelerated Structural Degeneration in Parkinson’s Disease
Objective: To compare the rate of global brain structural degeneration between healthy controls (HC) and patients with Parkinson’s disease (PD). Background: Normal aging is accompanied…Improving Equitable Access to Parkinson’s Disease Exercise Programs Through a Student-Led Transportation Model
Objective: To evaluate the feasibility and impact of a student-led transportation model designed to improve access to evidence-based exercise programs for people with Parkinson’s disease…Clinical Factors Associated with the Hospitalization of Patients with Parkinson’s Disease: A 3-year Prospective Study
Objective: This prospective study investigated the clinical factors associated with the hospitalization of patients with Parkinson’s disease (PD). Background: Patients with PD have higher hospitalization…Interpretable AI for Quantitative Video-Based UPDRS Assessment of Hand Movements in Parkinson’s Disease
Objective: To quantify and compare the diagnostic contributions of the three standard MDS-UPDRS hand motor tasks using video-based assessment of bradykinesia in Parkinson's Disease (PD).…SIRT3 upregulation in nigral dopaminergic neurons preserves motor circuit integrity for anti-sarcopenia
Objective: To determine whether enhancing resilience of substantia nigra dopaminergic neurons preserves motor circuit integrity. Background: Degeneration and dysfunction of substantia nigra pars compacta (SNpc)…
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