Morphometric assessment of age-associated neuronal changes in the human locus coeruleus
Objective: To delineate the age-related changes in the neuronal size and neuromelanin (NM) intensity in autopsied tissues of human locus coeruleus (LC). Background: Many studies…Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…Comparison in the disability level according to WHODAS 2 between people living with Early and Late Onset Parkinson’s Disease
Objective: To compare disability levels according to WHODAS-2 between people living with EOPD and people living with LOPD. Background: Although Parkinson's disease (PD) is more…The incidence of Parkinson’s disease in Nigeria: a systematic review and meta-analysis
Objective: The study aim to integrate various investigations pertaining to the incidence of Parkinson's disease (PD) in Nigeria, with the objective of comprehensively characterizing the…Applying the COM-B model to identify potential barriers for in-person on-site visits within the Healthy Brain Ageing (HeBA) study in Luxembourg
Objective: This study aims to (1) apply the Capability, Opportunity, and Motivation model of Behaviour (COM-B) to the HeBA online survey to identify potential barriers that could…Age-associated changes in the striatal proteins in aging Asian-Indians
Objective: To examine the age-related changes in tyrosine hydroxylase (TH), vesicular monoamine transporter2 (VMAT2), post-synaptic density protein-95 (PSD-95) and dopamine receptors (D1R, D2R) expression in the…Subjective cognitive decline and Frailty in an Asian cohort of patients with Parkinson’s Disease
Objective: To assess the prevalence of subjective cognitive decline (SCD) and to look for its association with frailty in an Asian cohort of patients with…Orthostatic hypotension and frailty
Objective: to investigate the relationship between functional class of orthostatic hypotension (FC OH) and frailty index (FI). Background: frailty syndrome (FS) as well as orthostatic…Subjective cognitive complaints in participants of the Healthy Brain Ageing (HeBA) study
Objective: To investigate the prevalence of subjective cognitive complaints (SCC) from Healthy Brain Ageing Study (HeBA) participants in Luxembourg, and explore risk factors prevalence which…GBA haplotypes and age at onset of Parkinson’s disease in the Asian population
Objective: To explore the involvement of GBA haplotypes in age at onset of Parkinson's disease in the Asian population. Background: GBA is an important risk…
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