MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Aging"

  • 2024 International Congress

    Rora deficiency aggravates dopamine neurons loss via reducing NAD+ level in Parkinson’s disease

    JW. Li, HS. Liu, XY. Hu, T. Wang, N. Xiong (Wuhan, China)

    Objective: To investigate the mechanism by which retinoic acid-related orphan receptor alpha(RORα) regulates NAD+ levels to dopamine neuronal degeneration in Parkinson’s Disease (PD). Background: PD is an age-related degenerative…
  • 2024 International Congress

    Simulated Space Gravity Recapitulates Parkinson’s Disease Pathology in Neural Cell Model

    V. Lentini, G. Uras, A. Manca, M. El Faqir, S. Lucas, A. Schapira, A. Pantaleo (Sassari, Italy)

    Objective: This investigation centers on the potential influence of microgravity on α-synuclein aggregation, a hallmark feature of Parkinson's disease (PD) characterized by the formation of…
  • 2023 International Congress

    The prevalence of Parkinson’s disease in a predominantly rural area of North West England

    R. Varden, R. Walker, A. O'Callaghan (Carlilse, United Kingdom)

    Objective: To calculate the crude and age adjusted prevalence of Parkinson’s disease (PD) in North Cumbria. Background: Prevalence data give insight into disease cause and…
  • 2023 International Congress

    Gemini digital twins identified neuro-common and disease-specific drivers of rate of change in NfL in Huntington’s disease, Parkinson disease and Alzheimer disease

    X. Shen, S. Sathe, L. Sun, P. Ashrap, K. Johnson, S. Sukhram, S. Reddy, S. Shin, J. Latourelle, C. Sampaio (Somerville, USA)

    Objective: Identify common and disease specific molecular drivers of rate of change in Neurofilament light (NfL) in Huntington’s disease (HD), Parkinson disease (PD) and Alzheimer…
  • 2023 International Congress

    Identification of pre-frailty in the elderly through serum metabolomics and its impact on Parkinson’s disease phenotype

    A. Imarisio, M. Avenali, G. Buongarzone, M. Picascia, T. Nuzzo, C. Gasparri, F. Errico, C. Marino, M. Grimaldi, MC. Monti, A. Filosa, M. Rondanelli, C. Pacchetti, AM. D'Ursi, A. Usiello, EM. Valente (Pavia, Italy)

    Objective: We attempted to better characterize pre-frailty using serum metabolomics in a large cohort of elderly subjects without neurodegenerative diseases. Next, we sought to investigate…
  • 2023 International Congress

    Epigenetic clocks suggest accelerated ageing in isolated REM Sleep Behavior Disorder patients

    L. Baldelli, C. Pirazzini, L. Sambati, F. Ravaioli, D. Gentilini, G. Calandra-Buonaura, P. Guaraldi, C. Franceschi, P. Cortelli, P. Garagnani, MG. Bacalini, F. Provini (Bologna, Italy)

    Objective: To investigate biological aging in videopolysomnography (vPSG)-confirmed isolated REM Sleep Behavior Disorder (iRBD) patients and vPSG-negative controls, using DNA methylation-based epigenetic clocks. Background: Isolated…
  • 2023 International Congress

    Caregiver burden in Parkinson disease: an updated scoping review

    J. Corcoran, W. Aamodt, S. Seshadri, M. Mirham, A. Job, S. Lettenberger, B. Kluger (Rochester, USA)

    Objective: We performed a scoping review to describe caregiver burden in Parkinson disease (PD) and build on the evidence provided by Mosely at al. [1]…
  • 2023 International Congress

    Detection of Camptocormia Using Ultrasound in Parkinson’s Disease

    R. Yilmaz, R. Wolke, N. Puls, M. Sorgun, G. Deuschl, D. Berg, N. Margraf (Ankara, Turkey)

    Objective: To investigate whether changes in the lumbar paravertebral muscles (LPM) can be detected using muscle ultrasonography (USG) in patients with Parkinson’s disease (PD, PwP)…
  • 2023 International Congress

    Associations between non-motor symptoms and patient characteristics in Parkinson’s disease: A multicenter cross-sectional study

    R. Morimoto, M. Iijima, Y. Okuma, K. Suzuki, F. Yoshii, S. Nogawa, T. Osada, K. Kitagawa (Tokyo, Japan)

    Objective: We aimed to investigate factors associated with non-motor symptoms (NMS) in Parkinson's disease (PD). Background: PD is characterized by a variety of NMS, such…
  • 2023 International Congress

    Dopaminergic Neuronal attributes in aging Substantia Nigra and Ventral Tegmental Area of mice strains distinctly sensitive to MPTP

    S. Choudhury, P L. Abhilash, P. Alladi (Bengaluru, India)

    Objective: To determine the age-related changes in neuronal morphology in the substantia nigra pars compacta (SNpc) and Ventral Tegmental Area (VTA) of C57BL/6J and CD-1…
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