How Parkinson’s Disease Research Has Shifted from 2016 – 2025 at the MDS Congress: A Topic-Based Analysis
Objective: Characterize temporal changes in PD research priorities presented at the MDS Congress from 2016 to 2025. Identify evolving thematic, methodological, and aging-related directions relevant…Sex Differences in Motor and Nonmotor Symptoms of De Novo Parkinson Disease by Age Group
Objective: While sex differences in Parkinson's disease (PD) are widely reported, data on how age influences these clinical variations are scarce. It is not fully…Functional Movement Disorders in Older Adults in Latin America: A Narrative Literature Review
Objective: To review the available literature on FMD in older adults (aged ≥ 65 years) in Latin America, focusing on epidemiology, clinical features, diagnostic challenges, treatment, and…SMR Combined with Multi Omics to Investigate the Mechanism of Action of the Cell Senescence Associated Gene (CDK2AP1) in Parkinson’s Disease
Objective: To identify novel cellular senescence-related genes in PD using multi-omics, determine causal relationships, predict mechanisms, and validate a key candidate in a rat model.…Epigenome-wide and gene-targeted epigenetic profile of isolated REM Sleep Behaviour Disorder: a clinico-molecular study
Objective: Comprehensively characterize the epigenetic profile of isolated REM Sleep Behaviour Disorder (iRBD) using genome-wide and gene-targeted approaches, linking it to clinical measures and phenoconversion.…Role of APOE Polymorphism and CSF Markers of AD Co-Pathology in the Cognitive Trajectories of Sporadic and Genetic Parkinson’s Disease: A Longitudinal Cohort Study
Objective: To evaluate if APOE genotype and CSF biomarkers of AD co-pathology are associated with distinct rates of cognitive decline in PD subtypes. Background: Cognitive…Comparison of clinical symptoms between young-onset and elderly-onset in patient with early Parkinson’s disease
Objective: We compared the clinical symptoms of early Parkinson's disease (PD) between young-onset and elderly-onset. Background: The progression of PD varies depending on the age…Epidemiology of Parkinson’s disease in Southern Brazil: Age- and Sex-Specific Findings from the PROBE-PD Study
Objective: To examine the prevalence of Parkinson’s disease and parkinsonism in individuals aged 60 years and older in a population-based sample from Southern Brazil, analyzing…Planning for the Parkinson’s Pandemic: Care needs in Australian Residential Aged Care Facilities
Objective: To evaluate the prevalence, demographic characteristics and care needs of people with Parkinson’s disease (PD) living permanently in residential aged care facilities (RACF) in…Ecologically Valid, Ambient, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Parkinson’s Disease (EVALUATE-PD)
Objective: To determine the feasibility of using in-home digital biomarkers (DBs) and activity monitoring for clinical trials and studies of early Parkinson’s Disease (PD) and…
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