Artificial Intelligence for Understanding Parkinson Disease State and Patient Stratification Using CSF Proteomics
Objective: The objective of this research is to employ an Artificial Intelligence (AI) approaches to identify patient status and disease states in neurodegenerative diseases (NDDs),…Safety Profile of Opicapone in Elderly and Very Elderly Population
Objective: This study aimed to characterize the safety profile of opicapone (OPC) in the elderly and compare post-marketing safety between (A) very elderly patients (≥…Dual-Task Cost of Walking While Using a Smartphone: A Comparison Study of Older Adults with and Without Cognitive Decline
Objective: To investigate spatiotemporal gait parameters in older adults with and without cognitive decline while walking in the presence of smartphone use. Background: The use…A pathology-validated study to investigate the role of Uric Acid in Parkinson’s Disease
Objective: The aim of this study is to compare plasma uric acid levels between pathology-confirmed and clinically misdiagnosed Parkinson’s disease patients at a single-patient level.…Exploring the Prevalence of Subjective Cognitive Decline and Mild Cognitive Impairment in Participants of the Luxembourg Healthy Ageing Study
Objective: Determine prevalence of Subjective Cognitive Decline(SCD) and Mild Cognitive Impairment(MCI) in participants of the Luxembourg Healthy Ageing(HeBA) Study. Background: Cognitive impairment can present as…Vegetables and fruits to relieve constipation: Do Parkinson’s disease patients know them?
Objective: To compare the knowledge of vegetables and fruits for treating constipation between PD and non-PD patients with constipation. Background: Constipation is a common non-motor…Subjective Cognitive Decline in a National Population-based probable RBD Survey
Objective: Examine the prevalence of Subjective Cognitive Decline (SCD) in a national population-based survey among participants at risk for RBD Background: SCD is defined as…A Post-mortem Study on Striatal Glia and Blood Brain Barrier Integrity in Aging and PD Asian-Indians.
Objective: We examined the glial and blood brain barrier (BBB) changes related to normal aging and PD in the Asian-Indian striatum. Background: increases the risk…PD in Tanzania: representative in city dwellers, absent in nomadic tribespeople?
Objective: To investigate the aetiology of PD demographically in an under researched region. Background: PD monogenic and susceptibility risk factors explain little to none of…Evaluation of Neurotransmitter and Co-transmitter Expression in the Aging Human Locus Coeruleus: Relevance to Neurodegenerative Disorders.
Objective: To analyze the age-associated changes in the neurotransmitter/co-transmitter expression and morphometric profiles of human locus coeruleus (LC) neurons using autopsied human tissues. Background: LC…
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