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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Apomorphine"

  • MDS Virtual Congress 2021

    Apomorphine infusion before subthalamic deep brain stimulation. A prospective comparative study in the same 20 patients.

    G. Fernández-Pajarín, A. Sesar, B. Ares, I. Jimenez-Martín, M. Gelabert-González, E. Arán-Echabe, JL. Relova, A. Castro (Santiago de Compostela, Spain)

    Objective: The objetive of this study was to compare the benefit of APO and STN-DBS in aPD in terms of motor (off daily hours, UPDRS…
  • MDS Virtual Congress 2021

    Deterioration in oral health status potentially associated with apomorphine pump initiation: a case report

    M. Auffret, V. Mathaut-Malefant, V. Denys, M. Tra, E. Boyer, V. Meuric, M. Bonnaure-Mallet, M. Vérin (Rennes, France)

    Objective: To describe the case of a patient with Parkinson’s disease (PD) who suffered from a rapid deterioration of his oral health status following treatment…
  • MDS Virtual Congress 2021

    Impact of device-aided therapies on QoL and Off-time improvement in advanced Parkinson’s Disease patients: Comparative effectiveness results from a Bayesian Network Meta-Analysis

    A. Antonini, R. Pahwa, P. Odin, S. Isaacson, A. Merola, L. Wang, P. Kandukuri, Y. Jalundhwala, A. Alobaidi, Y. Bao, C. Zadikoff, J. Parra, L. Bergmann, K. Chaudhuri (Padova, Italy)

    Objective: To compare off-time and QoL changes among APD patients taking LCIG, DBS, CSAI, and BMT at 6 months after therapy initiation. Background: Advanced Parkinson’s…
  • MDS Virtual Congress 2020

    A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results

    S. Factor, W. Ondo, S. Isaacson, P. Bhargava, B. Navia (Atlanta, GA, USA)

    Objective: Evaluate the long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s…
  • MDS Virtual Congress 2020

    Reduction of OFF time with apomorphine infusion during hours of pump use: Analysis from a Phase III, open-label study

    S. Isaacson, A. Espay, R. Pahwa, T. Clinch, P. LeWitt (Boca Raton, FL, USA)

    Objective: Evaluate the efficacy of apomorphine (APO) infusion in reducing OFF time during the hours of pump use in PD patients with motor fluctuations inadequately…
  • MDS Virtual Congress 2020

    Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Impact on Dyskinesia

    K. Klos, J. Hui, B. Robottom, P. Bhargava, B. Navia (Tulsa, OK, USA)

    Objective: Assess impact of apomorphine sublingual film (APL-130277; APL) on time spent with and functional impact of dyskinesia among patients with Parkinson’s disease (PD) and…
  • MDS Virtual Congress 2020

    A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in De Novo vs Rollover Patients With Parkinson’s Disease: Interim Results

    R. Pahwa, S. Fox, C. Singer, P. Bhargava, B. Navia (Kansas City, KS, USA)

    Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in de novo (DN) vs…
  • MDS Virtual Congress 2020

    Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Effect on MDS-UPDRS Part III Subdomains

    M. Siddiqui, V. Evidente, P. Bhargava, B. Navia, E. Pappert (Winston-Salem, NC, USA)

    Objective: Evaluate effect of apomorphine sublingual film (APL-130277; APL) as an on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD) on MDS-UPDRS Part…
  • MDS Virtual Congress 2020

    Dose Optimization of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients with Parkinson’s Disease: Clinical and Exposure Response Findings

    F. Stocchi, C. Olanow, E. Peckham, F. Agbo, Y. Chiu, K. Sciarappa, B. Navia (Rome, Italy)

    Objective: Evaluate if dose optimization (DO) of apomorphine sublingual film (APL-130277; APL) can achieve improved FULL “ON” response in patients with Parkinson’s disease (PD) and…
  • MDS Virtual Congress 2020

    A Discrete-Choice Experiment Evaluating Preferences for On-Demand Treatments for Patients with Parkinson’s Disease and “OFF” Episodes

    A. Thach, J. Sutphin, J. Coulter, C. Mansfield (Marlborough, MA, USA)

    Objective: To quantify patient preferences for on-demand treatments among patients with Parkinson’s disease (PD) and “OFF” episodes. Background: Patients with PD develop potentially disabling “OFF”…
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