Are we underestimating the dysautonomic burden in GBA related a-synucleinopathies?
Objective: The aim of the present study is to understand the prevalence of dysautonomic symptoms in a cohort of Italian glucocerebrosidase (GBA) mutated patients with…Prevalence and factors related to orthostatic hypotension and orthostatic intolerance in recently-diagnosed, drug-naïve Parkinson’s disease patients
Objective: To explore the prevalence and factors related to orthostatic hypotension (OH) and orthostatic intolerance (OI) in recently diagnosed drug-naïve PD patients from the Parkinson’s…Predictors of Orthostatic Hypotension in Patients with Parkinson’s Disease
Objective: To investigate factors that may affect blood pressure in patients with PD (Parkinson’s disease). Background: PD affects the autonomic nervous system, potentially leading to…Alterations of Blood Pressure Circadian Rhythm in Alpha-Synucleinopathies
Objective: To analyze the blood pressure (BP) circadian rhythm in Parkinson’s disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF), evaluating possible differences…A Comparative Study of Measured and Predicted Metrics of Respiratory Function in People with Parkinson’s Disease (PD)
Objective: The objective of this research was to compare measured metrics of respiratory function – Spirometry, Respiratory Muscle Strength and Peak Cough Flow – with…MIBG myocardial scintigraphy identifies premotor PD/DLB during a negative DAT scan period
Objective: It is unknown which marker is useful to identify the premotor phase PD/DLB. We recently reported four patients who, during a negative DAT scan…Changes in Supine Blood Pressure with Long Term Use of Droxidopa
Objective: To determine the long-term effects of droxidopa use on supine blood pressure (BP) in patients with neurogenic orthostatic hypotension (nOH). Background: nOH is a…The prevalence of supine hypertension and nocturnal hypertension and the difference of blood pressure in each sleep position in Parkinson’s disease
Objective: This study aimed to determine the prevalence, associated factors of SH/NH and to identify relationships between blood pressure (BP) and sleep position in PD…Population Pharmacokinetics and Pharmacodynamics of Ampreloxetine (TD-9855) in Patients with Neurogenic Orthostatic Hypotension (nOH)
Objective: To characterize the Phase 2 pharmacokinetics (PK) and pharmacodynamics (PD) of ampreloxetine in patients with nOH and provide dosing recommendations for special populations in…Autonomic dysfunction in early Parkinson’s disease: a prospective study
Objective: To define prevalence, severity, and predictors of dysautonomia symptoms in patients with Parkinson's disease (PD) recruited at the Hoehn and Yahr stage 1 prospectively followed for three years.…
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