Does the truth lie within the gut? Investigating the gut microbiome in an Australian cohort of Parkinson’s disease patients
Objective: Parkinson’s disease (PD) is associated with an assortment of difficult to recognize non-motor symptoms, including gastrointestinal (GI) dysfunction. Recently, there have been studies reporting…Dysautonomia as a predictor of cognitive outcome after deep brain stimulation in Parkinson’s disease
Objective: To evaluate cognitive effects of subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD) and to investigate whether subclinical autonomic dysfunction may…Ambulatory monitoring of electrodermal activity (EDA) and Heart Rate Variability (HRV) for prediction of motor fluctuations in Parkinson’s Disease (PD)
Objective: To determine whether changes in EDA and HRV are associated with motor fluctuations in patients with PD Background: EDA and HRV are affected in…Daily variability of non-motor symptoms as a reflection of circadian dysregulation in Parkinson’s disease
Objective: To assess the daily variability of visual and autonomic nervous system (ANS) functions in relation to sleep disorders to determine circadian PD phenotypes Background:…Differences in resting state fMRI distinguish multiple system atrophy and Parkinson disease
Objective: To investigate whether functional connectivity of the hypothalamus can distinguish multiple system atrophy from Parkinson disease. Background: Multiple system atrophy parkinsonian subtype (MSA-P) and…Deceleration capacity of heart rate: is cardiac vagal modulation impaired in idiopathic Parkinson’s disease?
Objective: Assessment of cardiac vagal modulation through the analysis of heart rate deceleration capacity (DC) in idiopathic Parkinson’s disease (PD). Background: Cardiac autonomic dysfunction manifests…Motor and Non-Motor Symptom Burden in Parkinsonian and Cerebellar Phenotypes of Probable MSA
Objective: We aimed to assess the disease severity, non-motor symptoms and cardiac autonomic dysfunction in MSA phenotypes. Background: Multiple system atrophy (MSA) is an adult-onset,…Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson’s disease
Objective: To characterize the gastrointestinal (GI) phenotype in the 6-hydroxydopamine (6OHDA) rat model of Parkinson’s disease (PD). Background: GI dysfunction, such as prolonged GI transit…Droxidopa and Midodrine Treatment Persistence in Patients with Orthostatic Hypotension
Objective: To determine the treatment persistence of droxidopa and midodrine in patients with orthostatic hypotension (OH) or neurogenic orthostatic hypotension (nOH) when medication cost was…Clinical heterogeneity of excessive daytime sleepiness in Parkinson’s disease
Objective: To examine reasons and associated clinical features of excessive daytime sleepiness (EDS) in patients with Parkinson’s disease (PD). Background: Patients with EDS can divided…
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