- Prevalence of Supine Hypertension in Alpha-Synucleinopathies: a Systematic Review and Meta-AnalysisObjective: We aimed to conduct a systematic review and meta-analysis to assess the prevalence of supine hypertension (SH) in α-synucleinopathies. Background: Alpha-synucleinopathies, including Parkinson’s Disease…
- Role of the UPSIT score in performing synucleinopathy diagnosisObjective: Determine if the UPSIT score is used to diagnose alpha-synucleinopathies and whether it correlates with neurogenic orthostatic hypotension (nOH). Background: Establishing a new diagnosis…
- Assessing the Relationship Between Autonomic Symptom Burden and Autonomic Failure in Parkinson’s DiseaseObjective: To examine the relationship between reported autonomic symptoms and autonomic failure identified by autonomic reflex testing in Parkinson’s disease (PD). Background: Autonomic failure is…
- Natural history and epidemiological study of multiple system atrophy in Hokkaido: HoRC-MSA 2014-2025Objective: To investigate epidemiological information of multiple system atrophy (MSA) patients in Hokkaido, Japan by using the registry data from the Hokkaido Rare-disease Consortium for…
- Characterization of autonomic dysfunction in prodromal and early stages of Parkinson’s DiseaseObjective: To evaluate cardiovascular autonomic dysfunction across prodromal stages of synucleinopathies (Pure Autonomic Failure-PAF); isolated REM Sleep Behavior Disorder-iRBD) and early stages of Parkinson’s disease…
- Is Urinary Retention a Marker of Possible Prodromal MSA in PAF?Objective: This study aims to evaluate the role of post-void urinary residual volume (PVR) in Pure Autonomic Failure (PAF) and its prognostic value as a…
- Motor & Non-Motor Symptoms in nOH & RBDObjective: To assess whether the co-occurrence of neurogenic orthostatic hypotension (nOH) and REM sleep behavior disorder (RBD) is associated with a more severe clinical presentation…
- Exploring Cardiac Autonomic Dysfunction in Synucleinopathies with Parkinsonism Across Awake-Sleep StagesObjective: To explore the differences in heart rate variability (HRV) across awake-sleep stages between patients with synucleinopathies and elderly controls without parkinsonism Background: A complex…
- Prevalence and Comorbidities of Orthostatic Hypotension in Older Adults: A Two-Year StudyObjective: To determine the prevalence of OH and its associations with autonomic dysfunction, falls, and mortality. Background: Orthostatic hypotension (OH) is a common problem that…
- Cardiac Autonomic Dysfunction in Patients with Multiple System Atrophy and Spinocerebellar Ataxia: A Comparative Study and Distinctive Machine Learning ModelObjective: To assess the differences of HRV parameters between MSA-C and SCA and their age-matched normal controls and also to use the supervised ML to…
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