Natural history and epidemiological study of multiple system atrophy in Hokkaido: HoRC-MSA 2014-2025
Objective: To investigate epidemiological information of multiple system atrophy (MSA) patients in Hokkaido, Japan by using the registry data from the Hokkaido Rare-disease Consortium for…Motor & Non-Motor Symptoms in nOH & RBD
Objective: To assess whether the co-occurrence of neurogenic orthostatic hypotension (nOH) and REM sleep behavior disorder (RBD) is associated with a more severe clinical presentation…Is Urinary Retention a Marker of Possible Prodromal MSA in PAF?
Objective: This study aims to evaluate the role of post-void urinary residual volume (PVR) in Pure Autonomic Failure (PAF) and its prognostic value as a…Exploring Cardiac Autonomic Dysfunction in Synucleinopathies with Parkinsonism Across Awake-Sleep Stages
Objective: To explore the differences in heart rate variability (HRV) across awake-sleep stages between patients with synucleinopathies and elderly controls without parkinsonism Background: A complex…Prevalence and Comorbidities of Orthostatic Hypotension in Older Adults: A Two-Year Study
Objective: To determine the prevalence of OH and its associations with autonomic dysfunction, falls, and mortality. Background: Orthostatic hypotension (OH) is a common problem that…Cardiac Autonomic Dysfunction in Patients with Multiple System Atrophy and Spinocerebellar Ataxia: A Comparative Study and Distinctive Machine Learning Model
Objective: To assess the differences of HRV parameters between MSA-C and SCA and their age-matched normal controls and also to use the supervised ML to…Autonomic Nervous System Dysfunction in Patients with Huntington’s Disease: Preliminary Results Using the COMPASS-31 Scale
Objective: To characterize dysautonomia-related symptoms in Huntington’s disease (HD) gene expansion carriers (HDGECs). Background: Autonomic nervous system (ANS) dysfunction is a recognized feature of HD…Improved Outcomes for Patients with Autonomic Movement Disorders (AMD) Originally Evaluated for Psychogenic Non-Epileptiform Spells (PNES)
Objective: To evaluate whether treating underlying dysautonomia in patients with abnormal movements initially diagnosed with psychogenic non-epileptiform spells (PNES) leads to a reduction in motor…A Rare Case of Dipeptidyl-peptidase-like protein 6 (DPPX) Antibody-Associated Encephalitis
Objective: To describe a case of DPPX antibody-associated encephalitis to facilitate early diagnosis and treatment. Background: DPPX antibody-associated encephalitis can be challenging to diagnose due…Clinical Progression and Genetic Pathways in Body-First and Brain-First Par-kinson’s Disease
Objective: We aim to assess Parkinson's disease (PD) phenotypes across both prodromal and clinical PD stages, track their pathological progression in vivo and identify potential underlying…
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