Intestinal transit in early-moderate Parkinson’s disease correlates with probable RBD – subclinical esophageal dysmotility does not correlate
Objective: To investigate esophageal and intestinal transit times in early-moderate Parkinson's disease (PD) and to study correlations with probable RBD and subjective symptoms. Background: Intraneuronal…Increased epinephrine in the saliva of Parkinson’s disease patients: A preliminary observation
Objective: To investigate the levels of dopamine (DA), norepinephrine (NE), epinephrine (EPI) and serotonin (5-HT) in the saliva of Parkinson’s disease (PD) patients and compare…Age and gender differences in cardiovascular autonomic failure in transgenic PLP-syn mouse model of multiple system atrophy
Objective: The main objective of the present study was to determine age and gender differences in measures of CAF in PLP-syn mice, a transgenic mouse…Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy
Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…131-MIBG is less promising in differentiating Parkinson’s disease from other parkinsonism for early onset patients
Objective: To investigate the diagnostic value of 131I-MIBG cardiac scintigraphy in differentiating PD from other parkinsonism for distinct age of onset. Background: MIBG cardiac sympathetic imaging has…Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson’s disease
Objective: To characterize the gastrointestinal (GI) phenotype in the 6-hydroxydopamine (6OHDA) rat model of Parkinson’s disease (PD). Background: GI dysfunction, such as prolonged GI transit…Long-term changes in myocardial sympathetic innervation and function in synucleinopathies
Objective: Describe long-term trends in indices of cardiac sympathetic innervation and function in synucleinopathies. Background: A group of neurodegenerative diseases including Parkinson disease (PD), pure…Is Heart Rate variability a differential biomarker in REM sleep behavior disorder, Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy?
Objective: Heart rate deceleration capacity (DC) and heart rate variability index (HRVI) as potential biomarkers for autonomic dysregulation were studied in subjects (each group N=10)…Degeneration of vagus nerve but not of accessory and phrenic nerve in Parkinson’s disease revealed by high-resolution ultrasound
Objective: To test the hypothesis that the vagus nerve is measurably atrophic in idiopathic Parkinson’s disease (PD). Background: The vagus nerve is discussed to represent…Are Lewy bodies associated with sympathetic pathology in dementia subjects?
Objective: Determine if Alzheimer disease (AD) subjects with Lewy bodies show sympathetic cardiac denervation. Background: Comorbid Lewy body (LB) pathology is very common in AD,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.