Machine Learning-Driven Analysis of Epigenetic Signatures in Juvenile Huntington’s Disease: Investigating Histone Modification Dynamics
Objective: To investigate the role of histone modifications in Juvenile Huntington’s Disease (JHD) using machine learning, aiming to identify novel epigenetic biomarkers predictive of disease…Strategies for Participant Retainment in Large Observational Studies in Movement Disorders: a Single Centre Experience
Objective: To explore common reasons for participant attrition and recruitment barriers in observational studies in people affected by movement disorders.To explore common reasons for participant…A Case report of Progressive Supranuclear Palsy with Cerebellar Ataxia and Chorea
Objective: To report a case of progressive supranuclear palsy cerebellar type (PSP-C) with choreiform movements. Background: PSP-C is a rare subtype of PSP characterized by…Reversible Uremic Striatopathy Presenting as Acute Generalized Myoclonus and Chorea in a Patient with End Stage Renal Disease: A video-case report
Objective: To highlight uremic striatopathy as a reversible metabolic cause of acute hyperkinetic movement disorder in patients with end stage renal disease. Background: Uremic striatopathy…Incidence and movement disorders associated with Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in the Princess Maha Chakri Sirindhorn Medical Center (MSMC)
Objective: To identify incidence and clinical features of SREAT patients in MSMC. Background: SREAT patients could present with encephalopathy with various neurological abnormalities, including behavioral…Suicidal Ideation and the Hippocampal Histaminergic System in Huntington’s Disease: A PET Study
Objective: To determine whether presence and severity of suicidal ideation (SI) are associated with hippocampal volume and histamine H3 receptor (H3R) PET uptake in people with Huntington’s disease (PwHD). Background: Suicidal ideation occurs in approximately 8–27% of PwHD, yet its causes remain unclear(1–3). The…Phenytoin Intoxication Masquerading as Generalized Chorea: A Case of Iatrogenic Double-Prescribing
Objective: To report a rare case of phenytoin-induced generalized chorea resulting from inadvertent medication duplication across multiple healthcare facilities, highlighting a preventable cause of acute…Intrinsic Suppression of the NRF2–Ferroptosis Defense Axis Defines Selective Vulnerability of D2-Striosome Neurons in Huntington’s Disease
Objective: This study mapped baseline stress-response and cell death programs in healthy human striatal populations to identify intrinsic molecular constraints in D2-striosome neurons and their…Late onset chorea secondary to antiphospholipid syndrome with radiological correlation on brain FDG-PET: a case report.
Objective: To describe chorea as the initial manifestation of antiphospholipid syndrome (APS) and its radiological correlation on brain FDG-PET as an autoimmune movement disorder. Background:…“Unexplained” Chorea Explained by Neuronal Antibodies: A Dutch Cohort Study
Objective: To identify neuronal antibodies in patients with unexplained chorea. Background: In recent years, autoimmune causes of chorea are increasingly recognized and the number of…
- 1
- 2
- 3
- …
- 9
- Next Page »