Gut problems in Huntington’s disease? Evidence for a leaky gut in the R6/2 mouse model of HD
Objective: This project aims to investigate how leaky the gut is in HD, why the gut is leaky, and how this relates to HD symptoms.…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…The History of Huntington Disease Description in Russia
Objective: The report provides detailed material on the history of the description of Huntington's disease (HD) in Russia. The first, unknown to a wide audience,…Cerebrospinal fluid proteomics reveals alterations of the renin-angiotensin system in Huntington’s disease
Objective: To identify new biomarkers of disease stage in HD. Background: Proteomic approaches for CSF studies in Huntington’s disease (HD) have so far yielded limited…White matter microstructural alterations in Huntington Disease: When neurodegeneration starts?
Objective: The aim of our study is to characterize in detail the white matter (WM) microstructure alterations in Huntington Disease (HD) using the diffusion tensor…The scaling properties of chorea and levodopa-induced dyskinesia are similar to voluntary movements
Objective: Explore whether levodopa-induced dyskinesia (LID) and chorea share voluntary movement characteristics to better understand the mechanisms underlying these involuntary movements. Background: We have recently…
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