Changes in GABAergic transmission of striatal neurons in presymptomatic Huntington’s Disease
Objective: To determine whether parameters of synaptic and extrasynaptic GABAergic inhibition of striatal projection neurons are altered in presymptomatic BACHD mice. Background: One attractive early…Pallidal surgery and physiological mechanism in choreic movements
Objective: To investigate the effect of deep brain stimulation (DBS) or coagulation of the internal globus pallidus (GPi) for choreic movements of various disorders and…The History of Huntington Disease Description in Russia
Objective: The report provides detailed material on the history of the description of Huntington's disease (HD) in Russia. The first, unknown to a wide audience,…Cerebrospinal fluid proteomics reveals alterations of the renin-angiotensin system in Huntington’s disease
Objective: To identify new biomarkers of disease stage in HD. Background: Proteomic approaches for CSF studies in Huntington’s disease (HD) have so far yielded limited…White matter microstructural alterations in Huntington Disease: When neurodegeneration starts?
Objective: The aim of our study is to characterize in detail the white matter (WM) microstructure alterations in Huntington Disease (HD) using the diffusion tensor…The scaling properties of chorea and levodopa-induced dyskinesia are similar to voluntary movements
Objective: Explore whether levodopa-induced dyskinesia (LID) and chorea share voluntary movement characteristics to better understand the mechanisms underlying these involuntary movements. Background: We have recently…
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