U-shaped dopamine resting state connectivity response function related to working memory performance in adults with early-stage Parkinson’s disease
Objective: Appraise how cognitive performance and neural response is affected by nigrostriatal denervation in early-stage Parkinson’s disease (PD). Background: Cognitive dysfunction in PD is heterogeneous…Cognitive profiling in patients with Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy: a 15-month longitudinal study
Objective: To characterize the progression of cognitive decline and compare the neuropsychological 15-month profile across PSP, MSA and PD. Background: Cognitive impairments are frequently reported in…Saccadic impairment in patients with Gaucher’s disease type 3
Objective: To characterize saccades in patients with chronic neuronopathic Gaucher’s disease (GD3) in relationship to their neurological and cognitive status using a computer-based eye-tracking technique. Background: GD3 is…Using eye tracking to identify pupil and saccade biomarkers of neurodegenerative disease
Objective: The Ontario Neurodegeneration Research Initiative Program (1) is investigating patients with neurodegeneration (Alzheimer’s disease: AD; mild cognitive impairment: MCI; Parkinson’s disease: PD; amyotrophic lateral…Self-awareness of cognitive functions in Parkinson’s disease patients with and without mild cognitive impairment.
Objective: To examine whether Parkinson’s disease (PD) patients with or without mild cognitive impairment (MCI) show impaired self-awareness (ISA) of their cognitive abilities. Background: PD…Subjective cognitive decline reflects recent cognitive change in non-demented patients with Parkinson’s disease
Objective: We investigated whether subjective cognitive decline (SCD) can reflect recent cognitive change in patients with Parkinson’s disease (PD) who had shown non-demented cognitive performance…The Effect of Anxiety on Cognition in Parkinson’s Disease
Objective: Our study examined the effect of anxiety on cognition in Parkinson’s disease (PD) patients without cognitive impairment, mild cognitive impairment and dementia. Background: Anxiety…Understanding neural activation in semantic fluency in Parkinson’s disease with mild cognitive impairment
Objective: To identify neural mechanisms relating to semantic fluency deficits in PD-MCI and to establish possible neuroimaging markers for Parkinson’s disease (PD) with dementia. Background:…Evaluation of SV2A expression with [18F]MNI-944 PET imaging in healthy controls (HC) and Parkinson disease (PD)
Objective: To evaluate [18F]MNI-944, a highly selective synaptic SV2A PET imaging tracer, as a biomarker for longitudinal studies in early PD. Background: PD symptoms manifest…General Anesthesia and Parkinson’s Disease
Objective: Postoperative cognitive dysfunction is common among the elderly. These changes may even be so severe that some elderly people actually become demented after undergoing…
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