Evaluating Cognitive Status in Parkinson’s Disease Using a Software-based Eye-Tracking Platform: Preliminary Results of the PALOMA Clinical Trial
Objective: To investigate the correlation between the cognitive status of Parkinson's disease (PD) patients and oculomotor parameters captured by a software-based eye-tracking platform using artificial…Cleaved plasma kininogen is associated with unfavorable cognitive outcome in Parkinson’s disease
Objective: The aim of this study was to examine the association between kininogen cleavage in plasma and cognitive outcome in Parkinson’s disease (PD). Background: No…Uncovering Non-Motor Subtypes in Parkinson’s Disease through Machine Learning
Objective: This study aims to uncover subtypes of Parkinson’s disease (PD) through unsupervised machine learning (ML), based on the predicted evolution of non-motor symptoms (NMS).…Efficacy of Novel A2A/A1 Antagonist in Motor and non-Motor Symptoms of MPTP-Treated Macaques
Objective: Our primary objective was to test the novel adenosine A2A/A1 receptor antagonist IDAA-338 in alleviating Parkinsonian symptoms when given as a mono or as…Cognitive Outcome in Pantothenate Kinase-Associated Neurodegeneration (PKAN) Treated with Deep Brain Stimulation (DBS):Case Report
Objective: To assess cognitive outcome in PKAN treated with DBS Background: PKAN is a rare neurodegenerative disorder with pediatric onset & dystonic features. Motor symptoms…SLC39A8-CDG with manganese deficiency in an adult individual: a case report
Objective: To report the case of an adult male with SLC39A8-CDG and evaluate the effects of manganese supplementation on clinical evolution of the patient. Background:…Exploring the Prevalence of Subjective Cognitive Decline and Mild Cognitive Impairment in Participants of the Luxembourg Healthy Ageing Study
Objective: Determine prevalence of Subjective Cognitive Decline(SCD) and Mild Cognitive Impairment(MCI) in participants of the Luxembourg Healthy Ageing(HeBA) Study. Background: Cognitive impairment can present as…The East London Parkinson Disease Project: updated results from engaging a diverse population in research
Objective: The East London Parkinson Disease (ELPD) project is a platform study aiming to understand the manifestations and determinants of Parkinson’s disease in a diverse…Characterisation and longitudinal significance of subjective cognitive decline in GBA and LRRK2 Parkinson’s disease
Objective: To investigate the clinical characteristics and predictive value associated with subjective cognitive decline (SCD) in people with Parkinson’s disease (PD) carrying pathogenic GBA or…Exploring the Root of Cognitive Decline in People Living with Parkinson’s Disease: An Analysis of MoCA Scores, Neuropsychiatric Symptoms, and Patient-Reported Outcomes
Objective: To evaluate cognitive decline in people living with PD (PwP), to determine to which degree different neuropsychiatric symptoms are risk factors for cognitive decline…
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