Subtyping Parkinson’s Disease Mild Cognitive Impairment (PD-MCI) by Cholinergic Degeneration
Objective: This study aims to investigate whether PD-MCI patients exhibiting cholinergic degeneration, evidenced by reduced Ch4 grey matter density (GMD) on brain MRIs, constitute a…Integrated Clinical Research Intern Program: Impact Upon Recruitment of Participants for Therapeutic Studies Aimed at Parkinson’s Disease (PD) Prevention.
Objective: To discuss the development and benefit of an online internship program created to expand recruitment and retention within a PD cohort and introduce students…Cholinergic Basal Forebrain Integrity and Cognition in Parkinson’s Disease
Objective: To examine the association between the integrity of the cholinergic basal forebrain (cBF) and cognition in Parkinson’s disease (PD). Background: Most PD patients experience…Comparative assessment of cognitive functions of patients with ET and ET plus.
Objective: to conduct a comparative analysis of changes in neurological status and cognitive decline of various types of essential tremor (ET). Background: in the new…Disease progression in Parkinson‘s disease patients with Mild Cognitive Impairment: 5-year longitudinal study from The Early Parkinson’s disease Longitudinal Singapore (PALS) cohort
Objective: To investigate motor, non-motor and cognition progression in early PD patients with Mild Cognitive Impairment (MCI) and normal cognition over 5 years. Background:…Visuo-spatial processing is linked to cortical glutamate dynamics in Parkinson’s disease – a 7 Tesla functional MRS study
Objective: To investigate alterations of glutamate metabolism in the occipital cortex during visual processing in patients with Parkinson’s disease (PD). Background: Cognitive decline is a…Musical Perception in Parkinson’s Disease, a Pilot Study
Objective: This pilot study aimed to investigate whether patients with PD have deficits in the perception of melody, rhythm, and musical excerpt recognition as measured…Gender-Specific Classification Models for Parkinson’s Disease using Non-Motor Symptoms and DNA Methylation Data
Objective: In Parkinson's disease (PD) non-motor symptoms often appear before the motor symptoms. Detecting and understanding these non-motor symptoms and their possible genetic or epigenetic…Reduced non-REM sleep in Parkinson disease is associated with memory impairment and non-motor symptom burden
Objective: To evaluate the relationship between sleep architecture and cognitive function in Parkinson disease (PD). Background: About half of PD patients develop mild cognitive impairment…Addition contact with 10 Hz stimulation in the STN may improve stimulation-induced cognitive disturbances
Objective: This case report demonstrates improvement of cognition by adding low-frequency stimulation in the ventral subthalamic nucleus (STN). Background: Deep brain stimulation (DBS) targeting the…
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