Frailty as clinical modulator of brain damage and progression in Parkinson’s disease
Objective: To evaluate the prevalence of frailty and correlation with motor and non-motor symptoms as well as MRI atrophy and white matter hyperintensities in Parkinson's…Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study
Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…APOE, TREM2 and LINGO1 genes: A possible implication in cognition in essential tremor in a Tunisian population
Objective: To investigate the effect of polymorphisms in APOE, TREM2 and LINGO1 genes on the cognitive profile of essential tremor(ET) in Tunisian population. Background: ET…Quantitative method for designing appropriate longitudinal follow-up frequency with application to Parkinson’s disease cognition research
Objective: To develop a quantitative method for designing appropriate longitudinal follow-up frequency. We demonstrate how to use this new method using a progression study of…Serum Neurofilament light chain levels and disability milestones in Lewy body diseases
Objective: To evaluate the relationship between motor, cognitive and autonomic symptoms and serum Neurofilament light chain levels in Lewy bodies disorders, namely Parkinson' s disease…The interplay between asymmetric dopaminergic degeneration, brain structural changes and cognition in de-novo PD: The PPMI dataset
Objective: To characterize the impact of asymmetric dopaminergic degeneration, measured with I123-ioflupane SPECT (DATSCAN), on cortical integrity and cognitive deficits, in de-novo right-handed PD patients.…Clinician Ratings of Cognition Predict Trajectory of Cognitive Decline in Newly Diagnosed Individuals with Parkinson’s disease
Objective: The overall goal of this study was to learn whether clinician ratings of cognition would predict trajectory of changes in memory performance over a…Cognitive impairment related networks of functional MRI in Parkinson’s disease
Objective: This study attempts to identify cognitive impairment related networks in the subjects with Parkinson’s disease using functional magnetic resonance imaging (MRI). Background: Voxelwise analysis…Cognitive profiling of patients with neurodegenerative disorders
Objective: To characterise the cognitive decline of patients with neurodegenerative disorders: Parkinson’s disease (PD), Alzheimer's disease (AD) and essential tremor (ET) and to compare their neuropsychological…Altered metabolic and functional resting state activity in cognitively unimpaired and impaired Parkinson’s disease patients
Objective: To assess the correspondence between functional connectivity and metabolic covariance in healthy controls and Parkinson’s disease patients (PD) with and without cognitive impairment. Background:…
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