Low Educational Level and Wilson’s disease: A direct path to cognitive decline
Objective: To assess cognitive profile of Wilson's Disease (WD) patients in a single tertiary Movement Disorders center in Fortaleza, Ceará, Brazil. Background: WD is an autosomal recessive disorder…Preclinical pharmacology and early clinical development of dopamine D1 positive allosteric modulators (D1PAMs) with therapeutic potential for neuropsychiatric disorders
Objective: The objective was to characterize novel dopamine D1PAMs pre-clinically in behavioral and neurochemical models and in phase 1 human studies in healthy volunteers and…The dual cognitive syndrome in Parkinson’s disease: volumetric, morphological and tractometric features
Objective: To assess volumetric, morphological and tractometric features associated with the fronto-striatal and posterior cortical cognitive profiles in Parkinson’s Disease (PD) Background: The dual syndrome…Predicting dementia in the first 6 years of Parkinson’s disease in the ICICLE-PD cohort
Objective: To determine which baseline cognitive tests in newly diagnosed participants with Parkinson’s disease (PD) predict conversion to dementia (PDD) within six years. Background: Cognitive…Exploring the role of the retrograde procedural memory in PD in the Luxembourg Parkinson’s Disease Study
Objective: Deepening knowledge of retrograde procedural memory (RPM) in typical Parkinson’s Disease (PD) patients to demonstrate that RPM is impaired in patients with PD. Background:…Candidate plasma miRNAs and EV protein as novel biomarkers in Parkinson’s disease patients with cognitive impairment and dementia
Objective: To determine the diagnostic value of circulating miRNAs and the extracellular vesicle proteins for early detection of patients with Parkinson’s disease and mild cognitive…Graph theory analysis of dopamine D2 receptor network in Parkinson’s disease patients
Objective: The aim of this study was to explore a novel method of analyzing positron emission tomography (PET) data using graph theory analysis. To this…Dysphasia as a novel approach for classification of speech disorders in Parkinson’s disease and other forms of neurodegeneration
Objective: To classify and identify the features of speech disorders in Parkinson's disease and other neurodegenerative diseases. Background: No unified approach to classification and diagnostics…Measure of Social Relation in Huntington’s Disease: The Relationship Self-Questionnaire (RSQ)
Objective: Development and validation of the Relationship Self-Questionnaire (RSQ), specific to Huntington’s disease (HD), which aims tomeasurepatients self-perceived quality of their relationships (RS). Background: In…Impulsivity and Compulsivity in Cerebellar Ataxias
Objective: To elucidate the role of human cerebellum in the reward processing system, of which a new cerebellar circuitry was recently identified in mice [1].…
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