Inhibition of long term memory and induction of biochemical deficits in rats following protofibrillar Aβ 1-42 injection
Objective: The present study was undertaken to study the effects of single intracerebroventricular (i.c.v.) injection of protofibrillar Aβ 1-42 on the long term memory Background:…Assessment of cognitive impairment using FP-CIT SPECT
Objective: We aimed to assess the cognitive impairment using FP-CIT SPECT in mild cognitive impairment or dementia patients. Background: In general, FP-CIT SPECT reflect pre-synaptic dopamine…The Impact of Cognitive Changes on Everyday Life for People with Parkinson’s: The Patient’s Perspective
Objective: To understand the patient’s perspective about cognitive changes in Parkinson’s disease and about the impact of cognitive dysfunction on daily life. Background: Cognitive dysfunction is…Action Verbal Fluency is Related to the Functional Integrity of the Cognitive Cortico-Striatal Loop in Parkinson’s Disease
Objective: The objective of this study is to investigate the relationship between action verbal fluency (the capacity to name as many action words as possible…Neurodegenerative biomarker abnormality frequency in idiopathic REM sleep behavior disorder
Objective: To describe the frequencies of neurodegenerative biomarker abnormalities in the adult Mayo Clinic iRBD prospective registry cohort. Background: The majority of patients with idiopathic…Effect of deep brain stimulation on visuospatial impairment in Parkinson’s disease
Objective: We evaluated postoperative change of visuospatial impairment in the patients with Parkinson’s disease (PD) underwent deep brain stimulation (DBS) to assess the impact of…Clinical characteristics of cognitive impairment in patients with Parkinson’s disease and its related pattern in 18F-FDG PET imaging
Objective: To characterize the clinical features and the neuroanatomical bases of cognitive impairment in Parkinson’s disease (PD) with respect to attention, executive function, memory, language,…Cognitive profiling in patients with Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy: a 15-month longitudinal study
Objective: To characterize the progression of cognitive decline and compare the neuropsychological 15-month profile across PSP, MSA and PD. Background: Cognitive impairments are frequently reported in…Saccadic impairment in patients with Gaucher’s disease type 3
Objective: To characterize saccades in patients with chronic neuronopathic Gaucher’s disease (GD3) in relationship to their neurological and cognitive status using a computer-based eye-tracking technique. Background: GD3 is…Using eye tracking to identify pupil and saccade biomarkers of neurodegenerative disease
Objective: The Ontario Neurodegeneration Research Initiative Program (1) is investigating patients with neurodegeneration (Alzheimer’s disease: AD; mild cognitive impairment: MCI; Parkinson’s disease: PD; amyotrophic lateral…
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