Determinants of Tremor Control Across Severity Levels Following GPi-Deep Brain Stimulation in Parkinson’s Disease
Objective: To compare clinical, stimulation-related, and anatomical determinants of tremor outcome after GPi DBS, between PD patients with severe and mild-moderate tremor. Background: Parkinson’s disease…Implementing Adaptive Deep Brain Stimulation in Parkinson’s Disease: A Multimodal Mixed-Methods Evaluation of a Pragmatic Clinical Workflow
Objective: The objective of this study is to evaluate a pragmatic clinical workflow and real-world implementation of adaptive Deep Brain Stimulation (aDBS) through integrated clinical,…Simulation Artifact in Complex Deep Brain Stimulation Patients
Objective: To describe stimulation artifacts in patients with complex deep brain stimulation hardware configurations and the impact on electrophysiology recordings. Background: Deep brain stimulation (DBS)…Subthalamic low-frequency activity reflects engagement during live sports viewing
Objective: To investigate subthalamic nucleus (STN) low-frequency dynamics during emotional engagement while watching live sports in patients with Parkinson's disease treated with adaptive deep brain…Reduction in Dopaminergic Medication in Patients with Parkinson’s Disease Treated with Continuous Apomorphine Infusion versus Subthalamic Nucleus Deep Brain Stimulation: A Cohort Study
Objective: To compare the reduction in levodopa equivalent daily dose (LEDD) in patients with Parkinson’s disease treated with continuous subcutaneous apomorphine infusion versus bilateral subthalamic…Beta and Gamma Local Field Potentials in Chronic Deep Brain Stimulation for Parkinson’s Disease: Programming Implications from a Systematic Review
Objective: To define distinct clinical roles of beta- and gamma-band local field potential (LFP) biomarkers in chronic deep brain stimulation (DBS) for Parkinson’s disease (PD)…Three-Year Results from the Largest Prospective Cohort of Directional Subthalamic Deep Brain Stimulation in Parkinson’s Disease to Date
Objective: To evaluate long-term real-world motor, quality-of-life, medication, and safety outcomes in patients with Parkinson’s disease (PD) treated with a multiple-independent-current-control (MICC) directional deep brain…Characterizing Local Field Potentials in Early-Onset Dystonia
Objective: To investigate the role of local field potential (LFP) recordings as biomarkers of dystonia severity in patients with pallidal deep brain stimulation (DBS) systems…Treatment of Bilateral Centromedian-Parafascicular (CM-Pf) Deep Brain Stimulation in a Pediatric Case of Rapid-Onset Dystonia-Parkinsonism
Objective: To report the negative outcome of bilateral centromedian-parafascicular (CM-Pf) DBS in a pediatric patient with drug-refractory Rapid-onset Dystonia-Parkinsonism (RDP) harboring an ATP1A3 mutation. Background:…Effect of deep brain stimulation on quality of life in Parkinson’s disease: a longitudinal analysis of clinical improvement and response probability using mixed-effects models and GEE
Objective: To evaluate the impact of deep brain stimulation (DBS) on quality of life (QoL) in patients with Parkinson’s disease (PD) by comparing PDQ-8 longitudinal…
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