Lead Asymmetry and Axial Symptom Response to Deep Brain Stimulation in Parkinson’s Disease: A Synthetic Pilot Modeling Study
Objective: To evaluate whether bilateral DBS lead placement asymmetry captures clinically meaningful correlates of motor outcomes, particularly freezing of gait (FoG) and balance to establish…Structural Brain Measures Predict Cognitive Performance After Deep Brain Stimulation for Parkinson’s Disease
Objective: To determine whether pre-operative brain morphometry, combined with baseline neuropsychological performance, can predict post-operative cognitive performance in PD patients undergoing DBS using a sparse…Event-Locked Characterization of Movement-Related Beta Modulation using Synchronized Local Field Potentials and Video-Based Kinematics
Objective: Identifying physiomarkers of PD motor function beyond total beta power by examining event-related subthalamic nucleus beta modulation during continuous finger tapping (FT) using synchronized…A case of difficulty extubating after General Anesthesia Deep Brain Stimulation (DBS) surgery
Objective: Dysfunction in speech, respiration, and swallowing can severely compromise the well-being of Parkinson’s disease (PD) patients. Here, we present a rare case of acute…An Optimized Workflow for High-Throughput RNA-Seq from Human Deep Brain Tissue Using DBS Microelectrodes
Objective: To optimize a workflow for extracting human deep brain RNA from DBS microelectrodes for transcriptome sequencing. Background: Understanding the molecular mechanisms of Parkinson’s disease…Long-Term Instability of GPi Gamma Oscillations in Parkinson’s Disease: A Case Study
Objective: To characterize longitudinal changes in globus pallidus internus (GPi) finely tuned gamma (FTG) oscillations during chronic deep brain stimulation (DBS) in a patient with…Should we really forget DBS in Parkinson’s Patients with Dementia?
Objective: To determine whether DBS is really an absolute contraindication in patients with Parkinson’s dementia. Background: It is well established in the literature that Parkinson’s…Real-World Clinical Outcomes of Adaptive versus Continuous Deep Brain Stimulation in Early-Stage Parkinson’s Disease: A Systematic Review and Meta-Analysis of 2024-2025 Trials
Objective: To evaluate the comparative efficacy, safety, and energy efficiency of adaptive deep brain stimulation (aDBS) versus continuous deep brain stimulation (cDBS) in Parkinson’s disease…Cognitive Trajectories After STN DBS in Parkinson’s Disease: 12-Month Outcomes
Objective: To determine whether early postoperative cognitive changes occur across distinct domains following STN-DBS Background: Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is…Application of the MDS Nonmotor-Symptom Questionnaire in Evaluation of Deep Brain Stimulation Candidates.
Objective: This study explores utility of the MDS Nonmotor-Symptom Questionnaire (MDS-NMS-Q) in neuropsychological evaluations of people with Parkinson’s disease (PwP) considering Deep Brain Stimulation (DBS).…
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