Randomized Controlled Trial Comparing Adaptive versus Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease; Closed Loop Optimization of Deep Brain Stimulation Effect in Parkinson’s Disease (CLOSE-PD study)
Objective: To evaluate whether adaptive deep brain stimulation (aDBS) of the subthalamic nucleus (STN) is more efficacious than continuous DBS (cDBS) in Parkinson's disease (PD)…The UF Adaptive Deep Brain Stimulation Experience
Objective: To describe our single center experience with implementing adaptive deep brain stimulation (aDBS) strategies into a high-volume neuromodulation center. Background: Adaptive deep brain stimulation…Clinical Outcomes of Globus Pallidus Interna Deep Brain Stimulation in Primary and Secondary Dystonia: A Single-Center Experience
Objective: To evaluate motor and disability outcomes following GPi-DBS in a mixed cohort of primary and secondary dystonia patients treated from a tertiary referral center…Body Weight Increases After DBS in Parkinson’s Disease but Not Essential Tremor
Objective: This retrospective longitudinal cohort study examined body weight trajectories surrounding unilateral and staged bilateral deep brain stimulation (DBS) across surgical targets in individuals with…Video-Based Gait Analysis for Objective Assessment of Motor Severity and Surgical Outcome in Parkinson’s Disease: A Scalable Alternative to Subjective Rating
Objective: To evaluate the accuracy of a gait-focused video analysis model in predicting clinical scores and post-surgical improvement in Parkinson’s disease (PD) Background: The MDS-UPDRS…Prospective International Registry Evaluating Real-World Clinical and Quality-of-Life Outcomes of Directional Deep Brain Stimulation in Essential Tremor
Objective: To assess real-world clinical effectiveness and patient-reported outcomes associated with a multiple independent constant current (MICC) directional deep brain stimulation (DBS) system in individuals…Probable RBD and Anxiety in Early Parkinson’s Disease Predict Subsequent Functionally Disabling Medication-Refractory Tremor
Objective: Functionally disabling, medication-refractory (FDMR) tremor is a key indication for device-aided therapy in Parkinson's disease (PD), yet baseline predictors remain poorly characterised. Background: PD…Experiences with Adaptive Deep Brain Stimulation for Parkinson’s Disease in Routine Clinical Care
Objective: To evaluate initial experiences and (symptom-specific) outcomes with adaptive deep brain stimulation (aDBS) for Parkinson’s disease (PD) in routine clinical care across multiple international…Multi-target Deep Brain Stimulation for Dystonia and Complex tremor syndromes: A Single-Centre Case Series and Literature Review
Objective: This clinical study highlights 10 cases treated at the Walton Centre NHS Foundation Trust (Liverpool, UK) wherein DBS has been implemented beyond unilateral and…Microstructure predicts cognition after Neurostimulation in Parkinson’s disease
Objective: To identify preoperative microstructural markers that are associated with postoperative changes in cognition. Background: Subthalamic deep brain stimulation (STN-DBS) represents an established therapeutic intervention…
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