Set_my_DBS: Multicenter study for the development of quantitative methods to support the programming of deep brain stimulation systems in patients with Parkinson’s disease.
Objective: To develop quantitative methods to assist clinicians in the programming of DBS systems, while establishing a consortium-based protocol among participating hospitals andcreating a secure…From Cerebral Palsy to GNAO1-Related Movement Disorder: An Adult Diagnosis with Marked Response to Pallidal Deep Brain Stimulation
Objective: To report a case initially diagnosed as cerebral palsy, later identified as a GNAO1 gene–related movement disorder and to illustrate the therapeutic impact of…Network determinants of stimulation-induced speech impairment after subthalamic DBS in Parkinson’s disease
Objective: To delineate hemisphere-specific, local, and network-level mechanisms underlying stimulation-induced speech impairment after subthalamic deep brain stimulation (STN-DBS). Background: STN-DBS can improve but also worsen…Cognitive Safety and Stability in DBS for Parkinson’s Disease: Evidence for the Inclusion of Patients with Baseline Mild Cognitive Impairment.
Objective: Investigate the cognitive safety of Deep Brain Stimulation (DBS) in PD patients with baseline pre-operative diagnosis of Mild Cognitive Impairment (MCI) Background: DBS is…Comparative Motor Response to Bilateral STN‑DBS in LRRK2‑Related and Idiopathic Parkinson’s Disease
Objective: To compare motor improvement after subthalamic nucleus deep brain stimulation (STN‑DBS) in patients with LRRK2‑associated Parkinson’s disease (PD) versus idiopathic PD (iPD). Background: LRRK2…Adaptive Subthalamic Nucleus Deep Brain Stimulation (aDBS) for Refractory Dyskinesia in Parkinson’s Disease: A Case Report of Two Patients
Objective: This is a case report of two patients to using adaptive subthalamic nucleus deep brain stimulation (aDBS) for refractory dyskinesia Background: Although continuous subthalamic…Neuroimaging-guided automated optimization of deep brain stimulation in Parkinson’s disease: preliminary results
Objective: To evaluate the clinical impact of an automated neuroimaging-guided optimization algorithm (Illumina™, Boston Scientific) for programming in patients with suboptimal response to subthalamic nucleus…Dorsal STN and Zona Incerta Stimulation as a Strategy to Reduce Dyskinesia after STN-DBS: A Case Series with Literature Reviews
Objective: These case series illustrate practical programming strategies and clinical decision-making in real-world DBS practice using the concept of stimulating the dorsal STN or ZI…Beta–motor state correspondence as a predictor of adaptive deep brain stimulation benefit in Parkinson’s disease
Objective: To clarify practical factors for optimizing adaptive deep brain stimulation (aDBS) to achieve better clinical outcomes in Parkinson’s disease (PD). Background: aDBS is a…Clinical and Mobility Outcome with Ring versus Directional Globus Pallidus Stimulation in Parkinson’s Disease
Objective: To compare therapeutic directional versus ring stimulation effects on clinical and objective mobility outcomes and beta band in people with Parkinson’s disease (PD) undergoing…
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