Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
Objective: We test the hypothesis of modulating subthalamic neuronal firing pattern via injection of hyperpolarizing current as an effective treatment for hyperkinetic movement disorders. Background:…Long-term quality of life after subthalamic deep brain stimulation depends on non-motor symptoms in Parkinson’s disease
Objective: To predict 36-month follow-up quality of life (QoL) outcome after bilateral subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease (PD). Background: STN-DBS improves…Euphoria-inducing lead contacts: mapping of image and electrophysiology in Parkinson’s disease
Objective: We characterized stimulation-induced euphoria during the programming of STN DBS. The lead contacts where euphoria was elicited were characterized anatomically and electrophysiologically. Background: Mood…A case report of myoclonus-dystonia with isolated myoclonus phenotype and novel mutation successfully treated with deep brain stimulation
Objective: Report the case of a patient with a novel SGCE gene mutation and isolated myoclonus phenotype who was successfully treated with deep brain stimulation…Treatment of medically refractory orthostatic tremor: deep brain stimulation of bilateral thalamic ventral intermediate nucleus with sustained symptomatic improvement
Objective: We describe a case of medically refractory orthostatic tremor successfully treated with deep brain stimulation in the ventral intermediate nucleus (Vim) of the thalamus.…Outcomes of a Prospective, Multicenter, International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: Here we report the collected outcomes from a large-scale registry of a deep brain stimulation (DBS) system capable of Multiple Independent Current Source Control…Impact of Deep Brain Stimulation on Fall Risk
Objective: To compare fall risk in Parkinson’s disease patients with and without deep brain stimulation of the subthalamic nucleus. Background: The prevention of falls is…Gpi Deep Brain Stimulation After Many Years of Subthalamic Nucleus Stimulation: Case Report
Objective: Management of motor complications after subthalamic nucleus (STN) deep brain stimulation (DBS) with globus pallidus interna (Gpi) stimulation. Background: Deep brain stimulation is an…Automated Capture of Deep Brain Stimulation Settings & Clinical Outcomes
Objective: To automate capture of deep brain stimulation (DBS) settings and clinical outcomes during programming for movement disorders. Background: DBS programming involves testing a wide…MR Conditional Labeling for DBS – Basic Physics for the Non-Specialist
Objective: A non-technical overview of the physics behind MR Conditional labeling for DBS devices and the implications for diagnostic imaging. Background: MRI is the recommended…
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