Genetic factors associated with dementia in Parkinson’s disease in the Parkinson’s Incidence Cohorts Collaboration (PICC)
Objective: To evaluate the effect of genetic variants in β-glucocerebrosidase (GBA), apolipoprotein E (APOE), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) loci on the risk…Morbidity and mortality from neurodegenerative patients hospitalized with COVID-19 in the Chicagoland area
Objective: To assess morbidity and mortality of acute COVID-19 infection in hospitalized patients with neurodegenerative diseases and compare with age-matched controls. Background: Outcomes from COVID-19…Quantitative method for designing appropriate longitudinal follow-up frequency with application to Parkinson’s disease cognition research
Objective: To develop a quantitative method for designing appropriate longitudinal follow-up frequency. We demonstrate how to use this new method using a progression study of…Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson’s disease patients with type 2 diabetes mellitus
Objective: Identifying the risk factors of dementia in patients with both Parkinson’s disease (PD) and type 2 diabetes mellitus (DM) (PD-DM) is clinically relevant and…Prion disease with 8 octapeptide repeat insertional mutation presenting with HDL1 phenotype
Objective: To report the clinical and genetic features in a patient with an insertion of 8 extra octapeptide repeats in the prion protein gene (PRNP).…Candidate plasma miRNAs and EV protein as novel biomarkers in Parkinson’s disease patients with cognitive impairment and dementia
Objective: To determine the diagnostic value of circulating miRNAs and the extracellular vesicle proteins for early detection of patients with Parkinson’s disease and mild cognitive…First Scientific Description of the Hepato-Lenticular Degeneration
Objective: Hepato-Lenticular Degeneration (HLD) first described by German pathologist Friedrich Theodor von Frerichs in 1854, but in the West it called Wilson's Disease. In Russia…Identification and clinical characteristics of Mild Cognitive Impairment in Parkinson’s disease
Objective: To examine the characteristics of mild cognitive impairment in Parkinson’s disease (PD) patients with mild cognitive impairment (MCI) Background: Cognitive disturbances in PD detrimentally…The usefulness of a dual-phase 18-F-FP-CIT PET in a case of Alzheimer’s disease with slow movement
Objective: To think about the usefulness of a dual-phase 18-F-FP-CIT PET in cases of dementia with bradykinesia. Background: A classic 18-F-FP-CIT PET is useful in…The ADNPC-RS: a risk score that identifies Lewy body disease individuals at risk for developing concomitant Alzheimer’s pathology
Objective: To identify which common genetic variants that confer risk for Alzheimer’s disease (AD) also predict the development of concomitant AD pathology in patients with…
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