Association of the GBA T369M polymorphism with motor and cognitive symptoms in Parkinson’s disease
Objective: To determine whether the GBA polymorphism T369M is associated with earlier age of onset, lower cognitive performance, and more severe motor impairment in Parkinson's…Use of pimavanserin in patients with Parkinson’s disease psychosis: Subgroup analysis of efficacy and safety in patients with and without cognitive impairment
Objective: A planned subgroup analysis of a phase 3 study was performed to evaluate the efficacy and safety of pimavanserin (PIM) in Parkinson’s disease psychosis…Self-awareness of cognitive functions in Parkinson’s disease patients with and without mild cognitive impairment.
Objective: To examine whether Parkinson’s disease (PD) patients with or without mild cognitive impairment (MCI) show impaired self-awareness (ISA) of their cognitive abilities. Background: PD…Rationale and Design of a Phase 2 Study to Evaluate the Efficacy of Intepirdine (RVT-101) in Improving Gait and Balance in Patients with Dementia
Objective: To describe the rationale and design of a Phase 2 study that evaluates the effect of intepirdine (RVT-101) on gait and balance in patients…Clinicopathological analysis of corticobasal syndrome: a retrospective study
Objective: Predicting underlying pathology in CBS. Background: Corticobasal syndrome (CBS) is pathologically heterogeneous. CBS is one of the clinical phenotypes of corticobasal degeneration (CBD) but may…Risk Factors for Dementia in Parkinson’s disease
Objective: To investigate putative risk factors for the development of dementia in patients with Parkinson’s disease. Background: Dementia in idiopathic Parkinson’s disease (PD) is a…Oscillatory Activity in the Nucleus Basalis of Meynert
Objective: Characterize oscillatory activity in and around the nucleus basalis of Meynert (NBM). Background: The NBM is the major source of cholinergic innervation to the…Changing patterns of intimate relationships as dementia emerges in Parkinson’s disease
Objective: To explore relationship satisfaction and aspects of intimacy in female partners of people with cognitive impairment associated with Parkinson’s disease (PD) using qualitative methods.…Ghrelin and the IGF-1 axis in cognitive impairment in PD
Objective: To explore the association of acyl-ghrelin (AG) levels with cognitive impairment (CI) in PD Background: Unintended weight loss (UWL) in PD is associated with…Resting state modulations of EEG low frequency bands in Parkinson’s disease.
Objective: Dynamics in EEG activity such as slowing in low-frequency bands has been reported in Parkinson’s disease (PD). The objective of the present study was…
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