Multimodal biomarkers as predictors of cognitive decline in Parkinson’s Disease
Objective: To identify a set of multimodal biomarkers to predict cognitive decline in non-demented Parkinson’s disease patients. Background: People with Parkinson’s Disease are at high…“Essential tremor” as a presenting symptom of neuronal intranuclear inclusion disease (NIID).
Objective: To describe a patient with late onset, sporadic NIID who had a tremor as his first complaint. Background: NIID is a rare, slowly progressive…Plasma Biomarkers in Idiopathic Normal Pressure Hydrocephalus
Objective: (1) To investigate the role of plasma biomarkers that is known to related to Alzheimer’s disease in INPH(2) To assess the diagnostic and prognostic…Prospective longitudinal CSF measurements and cognitive decline in GBA-associated Parkinsonism: not Abeta or Tau but Lewy body pathology?
Objective: To evaluate whether concomitant Ab and Tau pathology might contribute to the prominent cognitive decline in PD_GBA. Background: A considerable proportion of idiopathic Parkinson’s…Cerebrotendinous xanthomatosis without tendon xanthoma: a diagnostic challenge.
Objective: To describe the case of Cerebrotendinous xanthomatosis (CTX) without tendon xanthoma, highlighting the diagnostic challenge due to its rarity, as well as the importance…Genetic variations in Amyloid-beta1-42 clearance proteins determine onset of dementia in Parkinson’s disease and dementia with Lewy bodies
Objective: To evaluate whether genetic variants in genes known to be associated with Abeta1-42 clearance contribute to the interval between ages at onset of parkinsonism…Dementia in Parkinson’s disease is associated with increased diffusivity in amygdala and external capsule
Objective: To identify which regions are associated with dementia in Parkinson's disease (PD) brains. Background: Dementia is common in advanced PD and its early development…Chronic cerebral hypoperfusion accelerates cognitive dysfunction and microvascular impairment in the MPTP mouse model of Parkinson’s disease
Objective: To evaluate cerebral hypoperfusion on cognitive dysfunction and related microvascular impairment in the MPTP mouse model. Background: Vascular pathology and Parkinson's disease (PD) pathology…FYN expression is associated with regulatory region genetic variation
Objective: The hypothesis of this investigation was that FYN expression and promoter activity are significantly influenced according to genetic content. The objective of this investigation…Visual hallucinations may serve as a possible predictor for Parkinson’s disease dementia
Objective: To observe whether visual hallucinations serve as a predictor of Parkinson's disease dementia. Background: Visual hallucinations (VH) is one of non-motor symptoms in Parkinson's…
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