Apathy in de novo Parkinson’s disease improves after the first years with dopaminergic treatment.
Objective: to define the evolution of apathy and other neuropsychiatric symptoms in patients with early Parkinson’s disease (PD). Background: Apathy is a common neuropsychiatric symptom…Measuring Cortisol Levels in Persons with Huntington’s Disease
Objective: To assess subjective and objective measures of emotional stress via standardized scales and a physiological measure (salivary cortisol) in persons with Huntington’s Disease (HD)…The Clinical Landscape of Progressive Supranuclear Palsy in an Underserved Community from Southwestern Colombia
Objective: To elucidate the clinical presentation of Progressive Supranuclear Palsy (PSP) in a cohort residing in underserved communities in Buenaventura, Colombia—the country's primary maritime port…Characterizing Dopaminergic Correlates of Depression in Parkinson’s Disease: The PPMI Cohort
Objective: We explored the association between cerebrospinal fluid (CSF) dopamine metabolites and transporter denervation in the development of depression in Parkinson Disease (PD). Background: Depression…Validation of a New Patient-reported Outcome Scale for the Assessment of Essential Tremor
Objective: Develop and validate a TETRAS PRO subscale Background: The Essential Tremor Rating Assessment Scale (TETRAS) is a popular scale for essential tremor (ET), but…The assessment of anxiety and depression comorbidities and the DRN electrophysiology in a primate model of Parkinson’s Disease
Objective: The study aimed to examine the anxiety/depression-like phenotype and the potential role of dorsal raphe nucleus (DRN) in the gold standard primate model of…Assessing the Accuracy of Clinical features, CSF Dopamine Metabolites, and Striatal Binding Ratios for the Likelihood of Depression Over 10-year Follow Up in the PPMI Cohort.
Objective: To identify whether MDS-UPDRS scores, Dopamine Transporter (DaT) Striatal Binding Ratios (SBRs), or dopamine metabolites cerebrospinal fluid (CSF) concentrations could predict the likelihood of…Social phobia, anxiety and depression in patients with essential tremor
Objective: ET is the most diagnosed movement disorder, the frequency of which increases as a person ages. Background: To examine the incidence of social phobia,…Feasibility of a Web Application to Enable Social Interaction in the PREDICT-PD Cohort
Objective: This study aims to:(1) Explore the feasibility of delivering a web application to enable social interaction and analyse digital social characteristics.(2) Gather insights into…The comorbidity conundrum in functional movement disorder: How are FMD patients with additional other FND different?
Objective: This study aimed to compare patients with isolated Functional Movement Disorders [FMD-i] to those with associated co-morbid other Functional Neurological Disorders(FND) [FMD+]. Background: FMD…
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