Exploring the effects of torsinA dysfunction in an iPSC-derived neuronal model of TOR1A dystonia
Objective: To investigate phenotypic differences between iPSC-differentiated cortical neurons derived from patients with TOR1A dystonia compared to healthy controls. Background: Primary generalised dystonia is most…The Roche ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development – Focus on Parkinson’s disease
Objective: To develop an ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development to increase the probability of success of clinical trials in Parkinson’s disease. Background:…Motor Fluctuations development is associated with non-motor symptoms burden progression in Parkinson´s disease patients. A 2-year follow-up study.
Objective: The aim of the present study was to analyze the progression of non-motor symptoms (NMS) burden in Parkinson´s disease (PD) patients regarding the development…‘Top of the POPPS’ – how we set up an online support group for Partners of People with Parkinson’s.
Objective: To provide useful peer and professional support for partners of people with Parkinson's (PWP)To be able to offer that support in a Covid safe…Comparison of different risk scores for Parkinson’s disease in a population-based 10-year study
Objective: To validate the “enhanced” PREDICT-PD algorithm in a longitudinal population-based cohort and compare its performance with other Parkinson's disease risk scores in identifying cases…Improvement of movement disorder and neurodevelopment under selegiline in a CLTC deficient patient
Objective: We report the significative improvement on both movement disorder and neurodevelopment in a 5-year-old CLTC deficient patient treated with selegiline. Background: In 2019 we described a 30-year-old woman…Impact of the delayed diagnosis in the prognosis of Parkinson’s disease.
Objective: To evaluate the difference of motor and non-motor dysfunction, and quality of life in Parkinson’s disease (PD) patients with and without delayed diagnosis. Background:…A Novel Parkinson Shoe: A potential treatment of Unresponsive Freezing of Gait in Parkinson’s Disease Patients
Objective: To explore the effect of the novel PD shoe on FOG and gait parameters in PD patients with unresponsive FOG. Background: Freezing of gait (FOG) is…Combined Plantar Stimulations Using a Novel Parkinson Shoe benefit Parkinson’s Disease Patients with Unresponsive Freezing of Gait
Objective: To explore the effect of combined vibratory and pressure stimulations in PD patients with unresponsive FOG and develop the innovative PD shoe. Background: Freezing…Prognostic Modeling of Parkinson’s Disease Progression Using Early Longitudinal Patterns of Change
Objective: To develop a prognostic model using multiple longitudinal measures to predict temporal clinical progression in early PD. Background: Predicting time to Parkinson’s disease (PD)…
- « Previous Page
- 1
- 2
- 3
- 4
- 5
- 6
- …
- 10
- Next Page »