MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Disease-modifying strategies"

  • 2017 International Congress

    Physical Activity in Early Parkinson Disease

    S. Mantri, M. Fullard, J. Duda, J. Morley (Philadelphia, PA, USA)

    Objective: To characterize physical activity habits in patients with early Parkinson disease (PD). Background: Physical activity is an important therapy for PD as it may…
  • 2017 International Congress

    Preventing Levodopa Induced Dyskinesia with Docosohexanoid Acid in Parkinson Disease

    K. Chung, B. Lobb (Portland, OR, USA)

    Objective: The purpose of this study was to determine if Docosohexanoic acid (DHA) affects the speed and severity of development of levodopa induced dyskinesia (LID) in subjects starting levodopa (LD).…
  • 2017 International Congress

    Virtual research visits in individuals with Parkinson disease enrolled in a clinical trial: REACT-PD Study Interim Analysis

    C. Tarolli, K. Andrzejewski, M. Bull, S. Goldenthal, M. O'Brien, T. Simuni, G. Zimmerman, K. Biglan, E.R. Dorsey (Rochester, NY, USA)

    Objective: To demonstrate the feasibility, reliability, and value of conducting web-based clinical trial assessments in individuals with Parkinson disease (PD). Background: Increasing interest has been…
  • 2017 International Congress

    Multi-modal retention in a phase III clinical trial in early Parkinson disease (STEADY-PD III)

    B. Greco, T. Simuni, J. Denmark, S. Henderson, J. Lowell, S. Sharma, C. Tarolli, D. Young, K. Biglan (Rochester, NY, USA)

    Objective: To evaluate novel retention strategies in an ongoing phase 3 clinical trial in individuals with Parkinson disease (PD) Background: Adequate participant retention is a…
  • 2017 International Congress

    Drug utilization characteristics in individuals with early Parkinson’s disease interim analysis of the STEADY-PD III study

    S. Sharma, T. Simuni, B. Greco, K. Biglan, C. Tarolli, K. Hodgeman, D. Oakes, D. Penz (Rochester, NY, USA)

    Objective: To review symptomatic therapy (ST) utilization trends in individuals with early Parkinson’s disease (PD). Background: There are changing trends in ST utilization in early…
  • 2017 International Congress

    Case study: Real-time MRI articulatory comparison of a congenital aglossic and normal speaker

    B. McMicken (Irvine,  , CA, USA)

    Objective: Congenital aglossia is a rare syndrome of born without a tongue. This paper examines  articulatory movements of a congenital aglossic speaker to understand  physiology by…
  • 2017 International Congress

    The Critical Path for Parkinson’s Consortium: Understanding Motor Disease Progression Through Quantitative Medicine

    K. Romero, D. Conrado, B. Corrigan, K. Tsai, M. Ahamadi, S. Macha, V. Sinha, I. Watson, M. Bani, P. Muglia, V. Kern, C. Williams-Gray, D. Grosset, M. Hu, D. Burn, R. Lawson, K. Marek, A. Roach, D. Stephenson, T. Nicholas (Tucson, AZ, USA)

    Objective: Develop a quantitative tool to optimize the definition of entry criteria, enrichment strategies and stratification approaches, and submit for formal regulatory endorsement at FDA…
  • 2017 International Congress

    Treatable Rare Movement Disorders

    E. Gatto, H. Jinnah, A. Espay, J. Jankovic, K. Bhatia, M. Rodriguez, V. Fung, F. Cardoso, M. Rodriguez Oroz, A. Albanese, A. Muenchau, A. Chade, M. de Koning-Tijssen, M. Stamelou, P. Garcia Ruiz, C. Uribe Roca, F. Morgante, A. Dela Cerda, L. Schoels, J. Miyasaki, J. Ferreira (Buenos Aires, Argentina)

    Objective: To classify therapies of RMD into enzyme replacement therapy, specific dietary changes, avoidance or management of certain triggers, and  others Background: Rare diseases (RD)…
  • 2017 International Congress

    Disease-modifying effect of Zonisamide with the induction of BDNF and TrkB expression

    N. Kanzato (Haebaru-cho, Japan)

    Objective: To evaluate to predictors of the disease-modifying effect of drugs on Parkinson’s disease (DM-PD) according to long-term therapeutic investigation, especially regarding the non-dopaminergic agent…
  • 2017 International Congress

    Development of a prototype alpha-synuclein vaccine to induce T regulatory cells for the treatment of synucleonopathy

    E. Rockenstein, G. Ostroff, F. Dikengil, F. Rus, M. Mante, J. Florio, A. Adame, I. Trinh, E. Masliah, R. Rissman (La Jolla, CA, USA)

    Objective: Test the hypothesis that combining humoral and immunosuppressive cellular asyn immunization will enhance asyn clearance, and reduce inflammation and neuropathological symptoms in a human…
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