Efficacy and Safety of Mesdopetam (IRL790) for Levodopa Induced Dyskinesia in Parkinson’s Disease: A Meta analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of mesdopetam compared with placebo for levodopa‑induced dyskinesia (LID) in Parkinson’s disease (PD). Background: Mesdopetam (IRL790) is a…Receptor Selectivity Profile and Clinical Significance of Ecopipam and Its Metabolites as a Potential Therapy for Tourette Syndrome
Objective: To characterize the binding/inhibition and potential clinical relevance of ecopipam and its metabolites across a wide array of potential off-target receptors, ion channels, enzymes,…Dopamine Receptor Blocking Drug Exposure is Associated with Parkinson’s Disease
Objective: To test the hypothesis that dopamine receptor blocking agents (DRBAs) contribute to the later diagnosis of Parkinson’s disease (PD). Background: Recent evidence suggests that…Increased Health Care Utilization in Children/Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists: An Electronic Medical Records Database Analysis
Objective: To compare health care resource utilization (HCRU) in dopamine D2 receptor antagonist (D2RA)-exposed versus D2RA non-exposed individuals with Tourette syndrome (TS). Background: TS is…Real-World Adverse Event Profile in Children and Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists (D2RAs) Compared With Non-D2RAs
Objective: To further explore the safety profile of dopamine D2 receptor antagonists (D2RAs) for Tourette syndrome (TS) in a community setting. Background: D2RAs (aripiprazole/haloperidol/pimozide) are…Clinical Characteristics and Antipsychotic Medication Use in Pediatric Population Diagnosed With Tourette Syndrome
Objective: To assess the clinical characteristics and rate of antipsychotic medication discontinuation in a pediatric cohort diagnosed with Tourette syndrome (TS). Background: It is estimated…Scopolamine-induced Tardive Dyskinesia: A Case Report
Objective: To present a case of scopolamine-related Tardive Dyskinesia (TD) and review the documented anticholinergic-associated cases of TD and the underlying pathophysiology responsible for TD.…Efficacy and safety of Rotigotine Extended-Release Microspheres in Early Parkinson’s Disease
Objective: To assess the efficacy and safety of Rotigotine extended-release microspheres (LY03003) in patients with early Parkinson's disease Background: Treatment that provides a continuous flow of…Drug-induced parkinsonism with resting tremor
Objective: Resting tremor might be developed by long-term treatment of dopamine receptor antagonists in cases of drug-induced parkinsonism Background: Resting tremor is one of the…Parkinson’s disease in a Special Population -Diagnosis and treatment of Parkinson’s disease in cases of psychiatric disorders treated with dopamine receptors antagonists-
Objective: We studied diagnosis and treatment of Parkinson’s disease in cases of psychiatric disorders treated with dopamine receptors antagonists for a long time. Background: Schizophrenia…
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